Aspergillus fumigatus and Aspergillosis in 2019

JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

[HTML][HTML] The lung microbiome during health and disease

K Yagi, GB Huffnagle, NW Lukacs, N Asai - International journal of …, 2021 - mdpi.com
Healthy human lungs have traditionally been considered to be a sterile organ. However,
culture-independent molecular techniques have reported that large numbers of microbes …

Gut microbiota modulates COPD pathogenesis: role of anti-inflammatory Parabacteroides goldsteinii lipopolysaccharide

HC Lai, TL Lin, TW Chen, YL Kuo, CJ Chang, TR Wu… - Gut, 2022 - gut.bmj.com
Objective Chronic obstructive pulmonary disease (COPD) is a global disease characterised
by chronic obstruction of lung airflow interfering with normal breathing. Although the …

Advances in bronchiectasis: endotyping, genetics, microbiome, and disease heterogeneity

PA Flume, JD Chalmers, KN Olivier - The Lancet, 2018 - thelancet.com
Bronchiectasis is characterised by pathological dilation of the airways. More specifically, the
radiographic demonstration of airway enlargement is the common feature of a …

[HTML][HTML] The human respiratory system and its microbiome at a glimpse

L Santacroce, IA Charitos, A Ballini, F Inchingolo… - Biology, 2020 - mdpi.com
Simple Summary New data in the current scientific literature show that the composition of the
respiratory system microbiome differs in health and disease conditions and that the …

Obesity as a risk factor for COVID-19: an overview

RW Alberca, LM Oliveira, ACCC Branco… - Critical reviews in …, 2021 - Taylor & Francis
The current coronavirus disease-2019 (COVID-19) pandemic presents a huge challenge for
health-care systems worldwide. Many different risk factors are associated with disease …

Bronchiectasis

JD Chalmers, AB Chang, SH Chotirmall… - Nature reviews Disease …, 2018 - nature.com
Bronchiectasis refers to abnormal dilatation of the bronchi. Airway dilatation can lead to
failure of mucus clearance and increased risk of infection. Pathophysiological mechanisms …

The sputum microbiome, airway inflammation, and mortality in chronic obstructive pulmonary disease

AJ Dicker, JTJ Huang, M Lonergan, HR Keir… - Journal of Allergy and …, 2021 - Elsevier
Background The sputum microbiome has a potential role in disease phenotyping and risk
stratification in chronic obstructive pulmonary disease (COPD), but few large longitudinal …

[HTML][HTML] The lung microbiota: role in maintaining pulmonary immune homeostasis and its implications in cancer development and therapy

M Sommariva, V Le Noci, F Bianchi, S Camelliti… - Cellular and Molecular …, 2020 - Springer
Like other body districts, lungs present a complex bacteria community. An emerging function
of lung microbiota is to promote and maintain a state of immune tolerance, to prevent …

[HTML][HTML] New perspectives for mucolytic, anti-inflammatory and adjunctive therapy with 1, 8-cineole in COPD and asthma: review on the new therapeutic approach

LJ Juergens, H Worth, UR Juergens - Advances in therapy, 2020 - Springer
Abstract The mucolytic monoterpene 1, 8-cineole (eucalyptol), the major constituent of
eucalyptus species, is well known for its anti-inflammatory, antioxidant, bronchodilatory …