Targeted capture in evolutionary and ecological genomics
The rapid expansion of next‐generation sequencing has yielded a powerful array of tools to
address fundamental biological questions at a scale that was inconceivable just a few years …
address fundamental biological questions at a scale that was inconceivable just a few years …
Somatic genetic drift and multilevel selection in a clonal seagrass
All multicellular organisms are genetic mosaics owing to somatic mutations. The
accumulation of somatic genetic variation in clonal species undergoing asexual (or clonal) …
accumulation of somatic genetic variation in clonal species undergoing asexual (or clonal) …
Inference of distribution of fitness effects and proportion of adaptive substitutions from polymorphism data
The distribution of fitness effects (DFE) encompasses the fraction of deleterious, neutral, and
beneficial mutations. It conditions the evolutionary trajectory of populations, as well as the …
beneficial mutations. It conditions the evolutionary trajectory of populations, as well as the …
Current progress in evolutionary comparative genomics of great apes
A Yousaf, J Liu, S Ye, H Chen - Frontiers in Genetics, 2021 - frontiersin.org
The availability of high-quality genome sequences of great ape species provides
unprecedented opportunities for genomic analyses. Herein, we reviewed the recent …
unprecedented opportunities for genomic analyses. Herein, we reviewed the recent …
Natural selection in the great apes
A Cagan, C Theunert, H Laayouni… - Molecular biology …, 2016 - academic.oup.com
Natural selection is crucial for the adaptation of populations to their environments. Here, we
present the first global study of natural selection in the Hominidae (humans and great apes) …
present the first global study of natural selection in the Hominidae (humans and great apes) …
Comparison of the full distribution of fitness effects of new amino acid mutations across great apes
Castellano et al. provide the first comparison of the full distribution of fitness effects
(including deleterious, neutral but also beneficial mutations) in the great apes. The authors …
(including deleterious, neutral but also beneficial mutations) in the great apes. The authors …
Strong selective sweeps on the X chromosome in the human-chimpanzee ancestor explain its low divergence
The human and chimpanzee X chromosomes are less divergent than expected based on
autosomal divergence. We study incomplete lineage sorting patterns between humans …
autosomal divergence. We study incomplete lineage sorting patterns between humans …
polyDFEv2. 0: testing for invariance of the distribution of fitness effects within and across species
P Tataru, T Bataillon - Bioinformatics, 2019 - academic.oup.com
Distribution of fitness effects (DFE) of mutations can be inferred from site frequency spectrum
(SFS) data. There is mounting interest to determine whether distinct genomic regions and/or …
(SFS) data. There is mounting interest to determine whether distinct genomic regions and/or …
A whole-genome scan for evidence of recent positive and balancing selection in aye-ayes (Daubentonia madagascariensis) utilizing a well-fit evolutionary baseline …
The aye-aye (Daubentonia madagascariensis) is one of the 25 most endangered primate
species in the world, maintaining amongst the lowest genetic diversity of any primate …
species in the world, maintaining amongst the lowest genetic diversity of any primate …
Evidence that the rate of strong selective sweeps increases with population size in the great apes
Quantifying the number of selective sweeps and their combined effects on genomic diversity
in humans and other great apes is notoriously difficult. Here we address the question using …
in humans and other great apes is notoriously difficult. Here we address the question using …