Diverse applications of nanomedicine

B Pelaz, C Alexiou, RA Alvarez-Puebla, F Alves… - ACS …, 2017 - ACS Publications
The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …

Emerging micro-and nanotechnology based synthetic approaches for insulin delivery

R Mo, T Jiang, J Di, W Tai, Z Gu - Chemical society reviews, 2014 - pubs.rsc.org
Insulin is essential for type 1 and advanced type 2 diabetics to maintain blood glucose levels
and prolong lives. The traditional administration requires frequent subcutaneous insulin …

Hydrogels in emerging technologies for type 1 diabetes

S Fuchs, AU Ernst, LH Wang, K Shariati… - Chemical …, 2020 - ACS Publications
Type 1 diabetes therapies that afford tighter glycemic control in a more manageable and
painless manner for patients has remained a central focus of next-generation diabetes …

Nanodrugs: pharmacokinetics and safety

S Onoue, S Yamada, HK Chan - International journal of …, 2014 - Taylor & Francis
To date, various nanodrug systems have been developed for different routes of
administration, which include dendrimers, nanocrystals, emulsions, liposomes, solid lipid …

Potential of insulin nanoparticle formulations for oral delivery and diabetes treatment

CY Wong, H Al-Salami, CR Dass - Journal of controlled release, 2017 - Elsevier
Nanoparticles have demonstrated significant advancements in potential oral delivery of
insulin. In this publication, we review the current status of polymeric, inorganic and solid-lipid …

The influence of nanoparticle properties on oral bioavailability of drugs

Y Wang, C Pi, X Feng, Y Hou, L Zhao… - International journal of …, 2020 - Taylor & Francis
Oral administration has been the most common therapeutic regimen in various diseases
because of its high safety, convenience, lower costs, and high compliance of patients …

Nanoparticle delivery systems in the treatment of diabetes complications

EB Souto, SB Souto, JR Campos, P Severino… - Molecules, 2019 - mdpi.com
Diabetes mellitus, an incurable metabolic disease, is characterized by changes in the
homeostasis of blood sugar levels, being the subcutaneous injection of insulin the first line …

Efficient mucus permeation and tight junction opening by dissociable “mucus-inert” agent coated trimethyl chitosan nanoparticles for oral insulin delivery

M Liu, J Zhang, X Zhu, W Shan, L Li, J Zhong… - Journal of controlled …, 2016 - Elsevier
Oral administration of protein drugs is greatly impeded by the lack of drug carriers that can
efficiently overcome the absorption barriers of mucosa tissue, which consists of not only …

Antioxidant activities of chitosans and its derivatives in in vitro and in vivo studies

M Anraku, JM Gebicki, D Iohara, H Tomida… - Carbohydrate …, 2018 - Elsevier
This review focuses on the in vitro and in vivo antioxidant activities of various chitosan
preparations, including those with different molecular weights and degrees of acetylation …

[HTML][HTML] Multifunctional oral delivery systems for enhanced bioavailability of therapeutic peptides/proteins

Y Han, Z Gao, L Chen, L Kang, W Huang, M Jin… - … Pharmaceutica Sinica B, 2019 - Elsevier
In last few years, therapeutic peptides/proteins are rapidly growing in drug market
considering their higher efficiency and lower toxicity than chemical drugs. However, the …