Learning dynamical models of single and collective cell migration: a review
D Brückner, CP Broedersz - Reports on Progress in Physics, 2024 - iopscience.iop.org
Single and collective cell migration are fundamental processes critical for physiological
phenomena ranging from embryonic development and immune response to wound healing …
phenomena ranging from embryonic development and immune response to wound healing …
Tissue Active Matter: Integrating Mechanics and Signaling into Dynamical Models
DB Brückner, E Hannezo - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
The importance of physical forces in the morphogenesis, homeostatic function, and
pathological dysfunction of multicellular tissues is being increasingly characterized, both …
pathological dysfunction of multicellular tissues is being increasingly characterized, both …
Coordinated motion of epithelial layers on curved surfaces
L Happel, A Voigt - Physical Review Letters, 2024 - APS
Coordinated cellular movements are key processes in tissue morphogenesis. Using a cell-
based modeling approach we study the dynamics of epithelial layers lining surfaces with …
based modeling approach we study the dynamics of epithelial layers lining surfaces with …
Geometry adaptation of protrusion and polarity dynamics in confined cell migration
DB Brückner, M Schmitt, A Fink, G Ladurner… - Physical Review X, 2022 - APS
Cell migration in confining physiological environments relies on the concerted dynamics of
several cellular components, including protrusions, adhesions with the environment, and the …
several cellular components, including protrusions, adhesions with the environment, and the …
How multiscale curvature couples forces to cellular functions
Among the physicochemical cues in the cellular microenvironment that orchestrate cell
processes, the different levels of curvature in the extracellular matrix and intrinsic to the …
processes, the different levels of curvature in the extracellular matrix and intrinsic to the …
Polarization and motility of one-dimensional multi-cellular trains
Collective cell migration, whereby cells adhere to form multi-cellular clusters that move as a
single entity, play an important role in numerous biological processes, such as during …
single entity, play an important role in numerous biological processes, such as during …
A Vicsek-type model of confined cancer cells with variable clustering affinities
Z Kirchner, A Geohagan, A Truszkowska - Integrative Biology, 2024 - academic.oup.com
Clustering of cells is an essential component of many biological processes from tissue
formation to cancer metastasis. We develop a minimal, Vicsek-based model of cellular …
formation to cancer metastasis. We develop a minimal, Vicsek-based model of cellular …
The Mechanics of Building Functional Organs
TGR Andrews, R Priya - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
Organ morphogenesis is multifaceted, multiscale, and fundamentally a robust process.
Despite the complex and dynamic nature of embryonic development, organs are built with …
Despite the complex and dynamic nature of embryonic development, organs are built with …
Mesenchymal cell migration on one-dimensional micropatterns
Quantitative studies of mesenchymal cell motion are important to elucidate cytoskeleton
function and mechanisms of cell migration. To this end, confinement of cell motion to one …
function and mechanisms of cell migration. To this end, confinement of cell motion to one …