Development of the immune system and immunological protection in marsupial pouch young

JM Old, EM Deane - Developmental & Comparative Immunology, 2000 - Elsevier
At birth the tissues of marsupial immune system are underdeveloped. The young animal is
not immunocompetent. Histological and immunohistochemical studies of pouch young …

[HTML][HTML] The tammar wallaby: a marsupial model to examine the timed delivery and role of bioactives in milk

JA Sharp, S Wanyonyi, V Modepalli, A Watt… - General and …, 2017 - Elsevier
It is now clear that milk has multiple functions; it provides the most appropriate nutrition for
growth of the newborn, it delivers a range of bioactives with the potential to stimulate …

[HTML][HTML] Cathelicidins in the Tasmanian devil (Sarcophilus harrisii)

E Peel, Y Cheng, JT Djordjevic, S Fox, TC Sorrell… - Scientific reports, 2016 - nature.com
Tasmanian devil joeys, like other marsupials, are born at a very early stage of development,
prior to the development of their adaptive immune system, yet survive in a pathogen-laden …

[HTML][HTML] Characterisation of the koala (Phascolarctos cinereus) pouch microbiota in a captive population reveals a dysbiotic compositional profile associated with …

TI Maidment, ER Bryan, M Pyne, M Barnes, S Eccleston… - Microbiome, 2023 - Springer
Background Captive koala breeding programmes are essential for long-term species
management. However, breeding efficacy is frequently impacted by high neonatal mortality …

A review of complementary mechanisms which protect the developing marsupial pouch young

MJ Edwards, LA Hinds, EM Deane… - Developmental & …, 2012 - Elsevier
Marsupials are born without a functioning adaptive immune system, into a non-sterile
environment where they continue to develop. This review examines the extent of exposure …

[HTML][HTML] Host reproductive cycle influences the pouch microbiota of wild southern hairy-nosed wombats (Lasiorhinus latifrons)

S Weiss, D Taggart, I Smith, KM Helgen… - Animal Microbiome, 2021 - Springer
Background Marsupials are born much earlier than placental mammals, with most crawling
from the birth canal to the protective marsupium (pouch) to further their development …

An observational study of the microbiome of the maternal pouch and saliva of the tammar wallaby, Macropus eugenii, and of the gastrointestinal tract of the pouch …

KL Chhour, LA Hinds, NA Jacques… - Microbiology, 2010 - microbiologyresearch.org
Marsupial mammals, born in an extremely atricial state with no functional immune system,
offer a unique opportunity to investigate both the developing microbiome and its relationship …

Identification, characterization and expression of cathelicidin in the pouch young of tammar wallaby (Macropus eugenii)

KA Daly, MR Digby, C Lefévre, KR Nicholas… - … and Physiology Part B …, 2008 - Elsevier
Antimicrobial peptides, such as cathelicidin, are an evolutionarily old defense system.
However they have more complex actions than just simply their antimicrobial effects …

Analysis of the expression of immunoglobulins throughout lactation suggests two periods of immune transfer in the tammar wallaby (Macropus eugenii)

KA Daly, M Digby, C Lefèvre, S Mailer… - Veterinary Immunology …, 2007 - Elsevier
Marsupial young are born in an under-developed state without mature immune responses.
Prior to the maturation of an immune system, marsupial young are heavily reliant upon …

Tammar wallaby mammary cathelicidins are differentially expressed during lactation and exhibit antimicrobial and cell proliferative activity

SS Wanyonyi, JA Sharp, E Khalil, C Lefevre… - … and Physiology Part A …, 2011 - Elsevier
Cathelicidins secreted in milk may be central to autocrine feedback in the mammary gland
for optimal development in addition to conferring innate immunity to both the mammary …