The AMPK pathway in fatty liver disease

C Fang, J Pan, N Qu, Y Lei, J Han, J Zhang… - Frontiers in …, 2022 - frontiersin.org
Lipid metabolism disorders are the primary causes for the occurrence and progression of
various liver diseases, including non-alcoholic fatty liver disease (NAFLD) and alcoholic fatty …

B vitamins and one-carbon metabolism: implications in human health and disease

P Lyon, V Strippoli, B Fang, L Cimmino - Nutrients, 2020 - mdpi.com
Vitamins B9 (folate) and B12 are essential water-soluble vitamins that play a crucial role in
the maintenance of one-carbon metabolism: a set of interconnected biochemical pathways …

The liver as an endocrine organ—linking NAFLD and insulin resistance

MJ Watt, PM Miotto, W De Nardo… - Endocrine …, 2019 - academic.oup.com
The liver is a dynamic organ that plays critical roles in many physiological processes,
including the regulation of systemic glucose and lipid metabolism. Dysfunctional hepatic …

Glycine metabolism and its alterations in obesity and metabolic diseases

A Alves, A Bassot, AL Bulteau, L Pirola, B Morio - Nutrients, 2019 - mdpi.com
Glycine is the proteinogenic amino-acid of lowest molecular weight, harboring a hydrogen
atom as a side-chain. In addition to being a building-block for proteins, glycine is also …

Epigenetics, microRNA and metabolic syndrome: a comprehensive review

F Ramzan, MH Vickers, RF Mithen - International Journal of Molecular …, 2021 - mdpi.com
Epigenetics refers to the DNA chemistry changes that result in the modification of gene
transcription and translation independently of the underlying DNA coding sequence …

Betaine modulates oxidative stress, inflammation, apoptosis, autophagy, and Akt/mTOR signaling in methionine-choline deficiency-induced fatty liver disease

M Veskovic, D Mladenovic, M Milenkovic, J Tosic… - European journal of …, 2019 - Elsevier
We examined the effects of betaine, an endogenous and dietary methyl donor essential for
the methionine-homocysteine cycle, on oxidative stress, inflammation, apoptosis, and …

The association between non-alcoholic fatty liver disease (NAFLD) and advanced fibrosis with serological vitamin B12 markers: results from the NHANES 1999–2004

L Li, Q Huang, L Yang, R Zhang, L Gao, X Han, L Ji… - Nutrients, 2022 - mdpi.com
Background: There is evidence that vitamin B12 and associated metabolite levels are
changed in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis …

[HTML][HTML] Herbal medicines and nonalcoholic fatty liver disease

H Yao, YJ Qiao, YL Zhao, XF Tao, LN Xu… - World Journal of …, 2016 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD), which is characterized by excessive fat
accumulation in the liver of patients who consume little or no alcohol, becomes increasingly …

Hesperidin attenuates hepatic lipid accumulation in mice fed high-fat diet and oleic acid induced HepG2 via AMPK activation

H Chen, T Nie, P Zhang, J Ma, A Shan - Life Sciences, 2022 - Elsevier
Aims In recent years, more and more people are suffering from lifestyle-related disease such
as nonalcoholic fatty liver disease (NAFLD) because of unhealthy diet and lack of physical …

MDG-1, an Ophiopogon polysaccharide, restrains process of non-alcoholic fatty liver disease via modulating the gut-liver axis

X Wang, L Shi, X Wang, Y Feng, Y Wang - International journal of biological …, 2019 - Elsevier
Abstract MDG-1, a β-D-fructan polysaccharide extracted from the roots of Ophiopogon
japonicus, had preventive effect against obesity and hyperlipidemia in high-fat diet (HFD) …