Extracellular metabolism sets the table for microbial cross-feeding
The transfer of nutrients between cells, or cross-feeding, is a ubiquitous feature of microbial
communities with emergent properties that influence our health and orchestrate global …
communities with emergent properties that influence our health and orchestrate global …
Data-driven causal analysis of observational biological time series
AE Yuan, W Shou - Elife, 2022 - elifesciences.org
Complex systems are challenging to understand, especially when they defy manipulative
experiments for practical or ethical reasons. Several fields have developed parallel …
experiments for practical or ethical reasons. Several fields have developed parallel …
The microbial exometabolome: ecological resource and architect of microbial communities
AE Douglas - … Transactions of the Royal Society B, 2020 - royalsocietypublishing.org
All microorganisms release many metabolites, collectively known as the exometabolome.
The resultant multi-way cross-feeding of metabolites among microorganisms distributes …
The resultant multi-way cross-feeding of metabolites among microorganisms distributes …
Response of sugarcane rhizosphere bacterial community to drought stress
Sugarcane is an important sugar and energy crop, and its yield is greatly affected by
drought. Although a large number of studies have shown that rhizosphere microorganisms …
drought. Although a large number of studies have shown that rhizosphere microorganisms …
Simulations reveal challenges to artificial community selection and possible strategies for success
Multispecies microbial communities often display “community functions” arising from
interactions of member species. Interactions are often difficult to decipher, making it …
interactions of member species. Interactions are often difficult to decipher, making it …
Pleiotropic mutations can rapidly evolve to directly benefit self and cooperative partner despite unfavorable conditions
Cooperation, paying a cost to benefit others, is widespread. Cooperation can be promoted
by pleiotropic 'win-win'mutations which directly benefit self (self-serving) and partner (partner …
by pleiotropic 'win-win'mutations which directly benefit self (self-serving) and partner (partner …
Emergence and maintenance of stable coexistence during a long-term multicellular evolution experiment
The evolution of multicellular life spurred evolutionary radiations, fundamentally changing
many of Earth's ecosystems. Yet little is known about how early steps in the evolution of …
many of Earth's ecosystems. Yet little is known about how early steps in the evolution of …
Enhanced nutrient uptake is sufficient to drive emergent cross-feeding between bacteria in a synthetic community
RK Fritts, JT Bird, MG Behringer, A Lipzen… - The ISME …, 2020 - academic.oup.com
Interactive microbial communities are ubiquitous, influencing biogeochemical cycles and
host health. One widespread interaction is nutrient exchange, or cross-feeding, wherein …
host health. One widespread interaction is nutrient exchange, or cross-feeding, wherein …
Metabolic excretion associated with nutrient–growth dysregulation promotes the rapid evolution of an overt metabolic defect
In eukaryotes, conserved mechanisms ensure that cell growth is coordinated with nutrient
availability. Overactive growth during nutrient limitation (“nutrient–growth dysregulation”) can …
availability. Overactive growth during nutrient limitation (“nutrient–growth dysregulation”) can …
Systematic dissection of a complex gut bacterial community
AG Cheng, A Aranda-Díaz, S Jain, F Yu, M Iakiviak… - bioRxiv, 2021 - biorxiv.org
Efforts to model the gut microbiome have yielded important insights into the mechanisms of
interspecies interactions, the impact of priority effects on ecosystem dynamics, and the role …
interspecies interactions, the impact of priority effects on ecosystem dynamics, and the role …