Replication compartments of eukaryotic and bacterial DNA viruses: common themes between different domains of host cells
Subcellular organization is essential for life. Cells organize their functions into organelles to
concentrate their machinery and supplies for optimal efficiency. Likewise, viruses organize …
concentrate their machinery and supplies for optimal efficiency. Likewise, viruses organize …
The roles of nucleoid-associated proteins and topoisomerases in chromosome structure, strand segregation, and the generation of phenotypic heterogeneity in …
V Norris, C Kayser, G Muskhelishvili… - FEMS Microbiology …, 2023 - academic.oup.com
How to adapt to a changing environment is a fundamental, recurrent problem confronting
cells. One solution is for cells to organize their constituents into a limited number of spatially …
cells. One solution is for cells to organize their constituents into a limited number of spatially …
[HTML][HTML] Identifying the core genome of the nucleus-forming bacteriophage family and characterization of Erwinia phage RAY
A Prichard, J Lee, TG Laughlin, A Lee, KP Thomas… - Cell reports, 2023 - cell.com
We recently discovered that some bacteriophages establish a nucleus-like replication
compartment (phage nucleus), but the core genes that define nucleus-based phage …
compartment (phage nucleus), but the core genes that define nucleus-based phage …
Subcellular organization of viral particles during maturation of nucleus-forming jumbo phage
V Chaikeeratisak, K Khanna, KT Nguyen… - Science …, 2022 - science.org
Many eukaryotic viruses assemble mature particles within distinct subcellular compartments,
but bacteriophages are generally assumed to assemble randomly throughout the host cell …
but bacteriophages are generally assumed to assemble randomly throughout the host cell …
Phage-induced bacterial morphological changes reveal a phage-derived antimicrobial affecting cell wall integrity
T Soonthonsrima, HH Htoo, P Thiennimitr… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
In a looming post-antibiotic era, antibiotic alternatives have become key players in the
combat against pathogens. Although recent advances in genomic research allow scientists …
combat against pathogens. Although recent advances in genomic research allow scientists …
The intricate organizational strategy of nucleus-forming phages
A Prichard, J Pogliano - Current Opinion in Microbiology, 2024 - Elsevier
Nucleus-forming phages (chimalliviruses) encode numerous genes responsible for creating
intricate structures for viral replication. Research on this newly appreciated family of phages …
intricate structures for viral replication. Research on this newly appreciated family of phages …
DNA nanotechnology enhanced single-molecule biosensing and imaging
S Fu, T Zhang, H Jiang, Y Xu, J Chen, L Zhang… - TrAC Trends in Analytical …, 2021 - Elsevier
Single-molecule tools enable translating biorecognition events into electrical and optical
signals at the single-molecule level. However, the limitations such as poor specificity, low …
signals at the single-molecule level. However, the limitations such as poor specificity, low …
[HTML][HTML] Dye disaggregation light-up aptamer for super-resolution RNA imaging
C Yan, L Miao, Y Zhang, X Zhou, G Wang, Y Li… - Sensors and Actuators B …, 2023 - Elsevier
Genetically encoded light-up RNA aptamers have become powerful tools for visualizing
RNAs in cells. However, fluorogenic dye/aptamer pairs used for super-resolution RNA …
RNAs in cells. However, fluorogenic dye/aptamer pairs used for super-resolution RNA …
Inhibition of Mitochondrial ATP Synthesis and Regulation of Oxidative Stress Based on {SbW8O30} Determined by Single‐Cell Proteomics Analysis
L Gong, W Ding, Y Chen, K Yu, C Guo… - Angewandte Chemie …, 2021 - Wiley Online Library
The 10‐nuclear heteroatom cluster modified {SbW8O30} was successfully synthesized and
exhibited inhibitory activity (IC50= 0.29 μM). Based on proteomics analysis, Na4Ni2Sb2W2 …
exhibited inhibitory activity (IC50= 0.29 μM). Based on proteomics analysis, Na4Ni2Sb2W2 …
Bacteriophage lambda site‐specific recombination
GD Van Duyne, A Landy - Molecular microbiology, 2024 - Wiley Online Library
The site‐specific recombination pathway of bacteriophage λ encompasses isoenergetic but
highly directional and tightly regulated integrative and excisive reactions that integrate and …
highly directional and tightly regulated integrative and excisive reactions that integrate and …