Advances in understanding the role of dendritic cells in aplastic anaemia
M Gao, D Zhang, R Xu - Scandinavian Journal of Immunology, 2023 - Wiley Online Library
Aplastic anaemia (AA) is an autoimmune disease characterized by haematopoietic failure in
the bone marrow. Abnormal activation and hyperfunction of T lymphocytes are believed to …
the bone marrow. Abnormal activation and hyperfunction of T lymphocytes are believed to …
Immune checkpoints represent a promising breakthrough in targeted therapy and prognosis of myelodysplastic syndrome
X Guo, S Yu, X Ren, L Li - Heliyon, 2023 - cell.com
Myelodysplastic syndrome (MDS) is a hematological malignancy of undetermined etiology,
possibly linked to chromosomal structural alterations, genetic mutations, presentation and …
possibly linked to chromosomal structural alterations, genetic mutations, presentation and …
Multi-Omics Profiling Identifies Pathways Associated With CD8+ T-Cell Activation in Severe Aplastic Anemia
X You, Q Yang, K Yan, SR Wang, RR Huang… - Frontiers in …, 2022 - frontiersin.org
Severe aplastic anemia (SAA) is an autoimmune disease characterized by immune-
mediated destruction of hematopoietic stem and progenitor cells. Autoreactive CD8+ T cells …
mediated destruction of hematopoietic stem and progenitor cells. Autoreactive CD8+ T cells …
Increased IFN‐γ+ and TNF‐α+ mucosal‐associated invariant T cells in patients with aplastic anemia
X Chen, Y Zhang, Y Zhang, Y Zhang… - Cytometry Part B …, 2023 - Wiley Online Library
Background Aplastic anemia (AA) is known as an autoimmune disease in which T cell
activation is aberrant. It has been reported that unconventional T cells, mucosal‐associated …
activation is aberrant. It has been reported that unconventional T cells, mucosal‐associated …
STAT1 overexpression triggers aplastic anemia: a pilot study unravelling novel pathogenetic insights in bone marrow failure
AG Solimando, V Desantis, C Palumbo… - Clinical and …, 2023 - Springer
We identified STAT1 gain of function (GOF) in a 32-year-old female with pallor, weakness,
cough, and dyspnea admitted to our Division of Medicine. She had severe oral ulcers (OU) …
cough, and dyspnea admitted to our Division of Medicine. She had severe oral ulcers (OU) …
CD8+GITR+ T cells may negatively regulate T cell overactivation in aplastic anemia
G Huang, Y Zhang, X Wei, Z Yu, J Lai… - Immunological …, 2021 - Taylor & Francis
Aplastic anemia (AA) is a T cell immune-mediated autoimmune disease. Overactivated
CD8+ T cells play a leading role in the pathogenesis of AA, which may be due to disbalance …
CD8+ T cells play a leading role in the pathogenesis of AA, which may be due to disbalance …
Research Progress of Aplastic Anemia in Immune Dysfunction
Z Li, Z Zhou, Y Dai, L He, H Li - MEDS Clinical Medicine, 2022 - clausiuspress.com
Aplastic Anemia (AA) is an autoimmune disease mainly mediated by T cells. On the one
hand, focusing on the current research status of different T lymphocytes in AA. On the other …
hand, focusing on the current research status of different T lymphocytes in AA. On the other …