Drug-resistant mental disorders, particularly treatment-resistant depression, pose a
significant medical and social problem. To address this challenge, modern psychiatry is …

Intense interest surrounds current research on psychedelics, particularly regarding their
potential in treating mental health disorders. Various studies suggest a link between the …

The hypothalamus is an important component of the hypothalamic-pituitary-adrenal axis and
an important brain region of the limbic system. Twenty-four first depressive episode (FDE) …

Repetitive transcranial magnetic stimulation (rTMS) has shown efficacy and tolerability in
Major Depressive Disorder (MDD). However, the underlying mechanisms of its …

The treatment of severe depression remains a major challenge in the field of psychiatry.
Treatment resistance is defined as limited or no clinical response after two consequent …

Background: Treatment resistance impacts almost 50% of depression patients, with
amygdala dysfunction being widely implicated. The amygdala is a complex amalgamation of …

Psychiatric disorders have always attracted a lot of attention from researchers due to the
difficulties in their diagnoses and treatments. Molecular imaging, as an emerging …

Although there is a vast body of neuroscientific research on cognitive behavioral therapy
(CBT), many therapists are confused about how to incorporate the evidence into their clinical …

INFLAMMATORY CONTROL OF ANTIDEPRESSANT EFFICACY: AN IMAGING-GENETIC
APPROACH Page 1 UNIVERSITA’ VITA-SALUTE SAN RAFFAELE CORSO DI …