[HTML][HTML] Challenges and recent progress in oral drug delivery systems for biopharmaceuticals

B Homayun, X Lin, HJ Choi - Pharmaceutics, 2019 - mdpi.com
Routes of drug administration and the corresponding physicochemical characteristics of a
given route play significant roles in therapeutic efficacy and short term/long term biological …

Microfluidic fabrication of microparticles for biomedical applications

W Li, L Zhang, X Ge, B Xu, W Zhang, L Qu… - Chemical Society …, 2018 - pubs.rsc.org
Droplet microfluidics offers exquisite control over the flows of multiple fluids in microscale,
enabling fabrication of advanced microparticles with precisely tunable structures and …

[HTML][HTML] The additive manufacturing approach to polydimethylsiloxane (PDMS) microfluidic devices: review and future directions

A Tony, I Badea, C Yang, Y Liu, G Wells, K Wang, R Yin… - Polymers, 2023 - mdpi.com
This paper presents a comprehensive review of the literature for fabricating PDMS
microfluidic devices by employing additive manufacturing (AM) processes. AM processes for …

[HTML][HTML] Progress in the application of sustained-release drug microspheres in tissue engineering

L Ruan, M Su, X Qin, Q Ruan, W Lang, M Wu, Y Chen… - Materials Today Bio, 2022 - Elsevier
Sustained-release drug-loaded microspheres provide a long-acting sustained release, with
targeted and other effects. There are many types of sustained-release drug microspheres …

Functional profiling of circulating tumor cells with an integrated vortex capture and single-cell protease activity assay

M Dhar, JN Lam, T Walser… - Proceedings of the …, 2018 - National Acad Sciences
Tumor cells are hypothesized to use proteolytic enzymes to facilitate invasion. Whether
circulating tumor cells (CTCs) secrete these enzymes to aid metastasis is unknown. A …

Scaling up the throughput of microfluidic droplet-based materials synthesis: A review of recent progress and outlook

J Wu, S Yadavali, D Lee, DA Issadore - Applied Physics Reviews, 2021 - pubs.aip.org
The last two decades have witnessed tremendous progress in the development of
microfluidic chips that generate micrometer-and nanometer-scale materials. These chips …

Scalable fabrication and use of 3D structured microparticles spatially functionalized with biomolecules

S Lee, J de Rutte, R Dimatteo, D Koo, D Di Carlo - ACS nano, 2021 - ACS Publications
Microparticles with defined shapes and spatial chemical modification can interface with cells
and tissues at the cellular scale. However, conventional methods to fabricate shaped …

Recent advances in microgels: from biomolecules to functionality

Y Xu, H Zhu, A Denduluri, Y Ou, NA Erkamp, R Qi… - Small, 2022 - Wiley Online Library
The emerging applications of hydrogel materials at different length scales, in areas ranging
from sustainability to health, have driven the progress in the design and manufacturing of …

Droplet microfluidics for CTC-based liquid biopsy: a review

L Jiang, H Yang, W Cheng, Z Ni, N Xiang - Analyst, 2023 - pubs.rsc.org
Circulating tumor cells (CTCs) are important biomarkers of liquid biopsy. The number and
heterogeneity of CTCs play an important role in cancer diagnosis and personalized …

Step emulsification in microfluidic droplet generation: mechanisms and structures

Z Shi, X Lai, C Sun, X Zhang, L Zhang, Z Pu… - Chemical …, 2020 - pubs.rsc.org
The droplet-based microfluidic techniques have been applied widely in functional material
synthesis and biomedical information measurements, wherein step emulsification as an …