Treatment‐resistant major depressive disorder: Canadian expert consensus on definition and assessment

YE Rybak, KSP Lai, R Ramasubbu… - Depression and …, 2021 - Wiley Online Library
Background Treatment‐resistant depression (TRD) is a debilitating chronic mental illness
that confers increased morbidity and mortality, decreases the quality of life, impairs …

Efficacy, tolerability, and safety of toludesvenlafaxine for the treatment of major depressive disorder—A narrative review

O Vasiliu - Pharmaceuticals, 2023 - mdpi.com
The estimated rate of treatment-resistant major depressive disorder (TRD) remains higher
than 30%, even after the discovery of multiple classes of antidepressants in the last 7 …

[HTML][HTML] Optimizing the context of support of web-based self-help in individuals with mild to moderate depressive symptoms: a randomized full factorial trial

OT Bur, T Krieger, S Moritz, JP Klein… - Behaviour research and …, 2022 - Elsevier
Web-based self-help programs for individuals with depressive symptoms are efficacious.
Differences in effect sizes and adherence rates might be due to contextual factors. This …

Can machine learning be useful as a screening tool for depression in primary care?

EM de Souza Filho, HCV Rey, RM Frajtag… - Journal of Psychiatric …, 2021 - Elsevier
Depression is a widespread disease with a high economic burden and a complex
pathophysiology disease that is still not wholly clarified, not to mention it usually is …

Temporal associations between depressive features and self-stigma in people with substance use disorders related to heroin, amphetamine, and alcohol use: a cross …

M Saffari, KC Chang, JS Chen, CW Chang, IH Chen… - BMC psychiatry, 2022 - Springer
Background Depression is a mental health problem and substance use concerns are
socially unacceptable behaviors. While depression and substance use may individually …

Prevalence and factors associated with subclinical hypothyroidism in major depressive disorder patients with dyslipidemia

L Zhan, H Yin, Y Gao, Y Li, J Ma - Neuropsychiatric Disease and …, 2023 - Taylor & Francis
Background Major depressive disorder (MDD) is a common psychiatric disorder with a high
prevalence of comorbidity with subclinical hypothyroidism. The aim of this study was to …

Association of non-HDL-C and depression: a cross-sectional analysis of the NHANES data

X Zhu, Y Zhao, L Li, J Liu, Q Huang, S Wang… - Frontiers in …, 2023 - frontiersin.org
Objectives Non-high-density lipoprotein cholesterol (non-HDL-C) has attracted attention
because it is associated with a variety of diseases and is easy to measure. However, the …

The effect of repetitive transcranial magnetic stimulation on suicidal ideation in treatment-resistant depression: a meta-analysis

S Mehta, G Konstantinou, CR Weissman… - The Journal of clinical …, 2022 - psychiatrist.com
Objective: To quantitatively synthesize the literature on the effects of repetitive transcranial
magnetic stimulation (rTMS) on suicidal ideation (SI) in patients with treatment-resistant …

Cost–effectiveness of combinatorial pharmacogenomic testing for depression from the Canadian public payer perspective

JA Tanner, PE Davies, CC Overall, D Grima… - …, 2020 - Taylor & Francis
Aim: Evaluate the cost–effectiveness of combinatorial pharmacogenomic (PGx) testing,
versus treatment as usual (TAU), to guide treatment for patients with depression, from the …

Association between changes in handgrip strength and depression in Korean adults: a longitudinal panel study

H Kim, W Jeong, SH Kim, YS Park, SI Jang, EC Park - Scientific reports, 2022 - nature.com
Depression in older adults is a global socioeconomic burden. Identifying factors, such as
physical activity or exercise that can help prevent depression is important. We aimed to …