Phosphoinositides (PIs) make up only a small fraction of cellular phospholipids, yet they
control almost all aspects of a cell's life and death. These lipids gained tremendous research …

Enteric Escherichia coli (E. coli) are both natural flora of humans and important pathogens
causing significant morbidity and mortality worldwide. Traditionally enteric E. coli have been …

The plasma membrane and the underlying cortical actin cytoskeleton undergo continuous
dynamic interplay that is responsible for many essential aspects of cell physiology …

The human pathogens enteropathogenic and enterohemorrhagic Escherichia coli (EPEC
and EHEC) share a unique mechanism of colonization that results from the concerted action …

Intracellular pathogens subvert the host cell cytoskeleton to promote their own survival,
replication, and dissemination. Study of these microbes has led to many discoveries about …

Professional phagocytes provide immunoprotection and aid in the maintenance of tissue
homeostasis. They perform these tasks by recognizing, engulfing and eliminating pathogens …

Lipids were long believed to have a structural role in biomembranes and a role in energy
storage utilizing cellular lipid droplets and plasma lipoproteins. Research over the last …

A variety of microbes manipulate the cytoskeleton of mammalian cells to promote their
internalization, motility and/or spread. Among such bacteria, enteropathogenic Escherichia …

Subversion of host membrane machinery is important for the uptake, survival, and
replication of bacterial pathogens. Understanding how pathogens manipulate host …

Tight junctions (TJs) are sealing complexes between adjacent epithelial cells, functioning by
controlling paracellular passage and maintaining cell polarity. These functions of TJs are …