Graphene oxide (GO) was initially developed to emulate graphene, but it was soon
recognized as a functional material in its own right, addressing an application space that is …

N 6-Methyladenosine (m6A) is the most prevalent internal modification on mRNA and
represents a new layer of gene expression in eukaryotes. The field of m6A-encoded …

Abstract N 6-Methyladenosine (m 6 A) is a reversible chemical modification in eukaryotic
messenger RNAs and long noncoding RNAs. The aberrant expression of RNA …

Fat mass and obesity-associated enzyme (FTO) can dynamically regulate N 6-
methyladenosine modification, and it is engaged in various cellular functions. Herein, we …

Graphene oxide (GO), an oxidized derivative of graphene, has received much attention for
developing novel fluorescent bioanalytic platforms due to its remarkable optical properties …

Gene methylation-related enzymes (GMREs) are disfunction and aberrantly expressed in a
variety of cancers, such as lung, gastric, and pancreatic cancers and have important …

FTO mediates oxidation demethylation of different RNA types and regulates fat mass and
adipogenesis. More and more evidences show that FTO is deeply involved in the …

The m6A demethylase catalyzes the removal of m6A modification to establish proper RNA
methylation patterns, and it has emerged as a promising disease biomarker and a …

In this work, a smart nanoplatform responding to multiple biomarkers has been developed
for the real-time tracking of the intracellular delivery of a 2D nanosystem. Our work provides …

We develop for the first time a label-free fluorescent method for sensitive detection of fat
mass and obesity-associated protein (FTO) activity using MazF-mediated primer generation …