Leprosy: a review of epidemiology, clinical diagnosis, and management

KH Chen, CY Lin, SB Su… - Journal of Tropical …, 2022 - Wiley Online Library
Leprosy is a neglected infectious disease caused by acid‐fast bacillus Mycobacterium
leprae. It primarily affects the skin and then progresses to a secondary stage, causing …

[PDF][PDF] Guidelines for the diagnosis, treatment and prevention of leprosy

World Health Organization - 2018 - apps.who.int
The Guidelines for the Diagnosis, Treatment and Prevention of Leprosy providestate-of-the-
art knowledge and evidence on leprosy diagnosis, treatment andprevention based on a …

PCR-based techniques for leprosy diagnosis: from the laboratory to the clinic

AN Martinez, C Talhari, MO Moraes… - PLoS Neglected …, 2014 - journals.plos.org
In leprosy, classic diagnostic tools based on bacillary counts and histopathology have been
facing hurdles, especially in distinguishing latent infection from active disease and …

Isolation of Mycobacterium lepromatosis and Development of Molecular Diagnostic Assays to Distinguish Mycobacterium leprae and M. lepromatosis

R Sharma, P Singh, RC McCoy, SM Lenz… - Clinical Infectious …, 2020 - academic.oup.com
Background Mycobacterium leprae was thought to be the exclusive causative agent of
leprosy until Mycobacterium lepromatosis was identified in a rare form of leprosy known as …

[HTML][HTML] Diagnostic accuracy of tests for leprosy: a systematic review and meta-analysis

P Gurung, CM Gomes, S Vernal… - Clinical Microbiology and …, 2019 - Elsevier
Objectives Owing to difficulties in the clinical diagnosis of leprosy, several complementary
tests have been developed and used. The aim was to systematically summarize the …

Neuropathies of leprosy

SV Khadilkar, SB Patil, VP Shetty - Journal of the neurological sciences, 2021 - Elsevier
Neuropathies form an integral part of the symptomatology of leprosy. Neuropathies of
leprosy take various forms and shapes. At one end is the cutaneous nerve involvement …

Blood RNA signature RISK4LEP predicts leprosy years before clinical onset

M Tió-Coma, SM Kiełbasa, SJF van den Eeden… - …, 2021 - thelancet.com
Background Leprosy, a chronic infectious disease caused by Mycobacterium leprae, is often
late-or misdiagnosed leading to irreversible disabilities. Blood transcriptomic biomarkers …

Mycobacterium leprae genomes from naturally infected nonhuman primates

TP Honap, LA Pfister, G Housman, S Mills… - PLoS neglected …, 2018 - journals.plos.org
Leprosy is caused by the bacterial pathogens Mycobacterium leprae and Mycobacterium
lepromatosis. Apart from humans, animals such as nine-banded armadillos in the Americas …

[HTML][HTML] Pure neuritic leprosy: Current status and relevance

PN Rao, S Suneetha - Indian Journal of Dermatology, Venereology and …, 2016 - ijdvl.com
Pure neuritic leprosy has always been an enigma due to its clinical and management
ambiguities. Although only the Indian Association of Leprologist's classification recognizes' …

Genomic Characterization of Mycobacterium leprae to Explore Transmission Patterns Identifies New Subtype in Bangladesh

M Tió-Coma, C Avanzi, EM Verhard… - Frontiers in …, 2020 - frontiersin.org
Mycobacterium leprae, the causative agent of leprosy, is an unculturable bacterium with a
considerably reduced genome (3.27 Mb) compared to homologues mycobacteria from the …