Melatonin and respiratory diseases: a review

S Habtemariam, M Daglia, A Sureda… - Current topics in …, 2017 - ingentaconnect.com
Melatonin is an indoleamine with potent multifunctional biological and pharmacological
effects, both receptor dependent and receptor-independent effects, including antioxidant …

Inflammation in venous thromboembolism: cause or consequence?

A Saghazadeh, S Hafizi, N Rezaei - International immunopharmacology, 2015 - Elsevier
Venous thromboembolism (VTE) which includes deep vein thrombosis (DVT) and
pulmonary thromboembolism (PTE) is a moderately common disease especially in elderly …

Upregulation of inflammatory cytokines in pulmonary embolism using biochip-array profiling

E Bontekoe, Y Brailovsky… - Clinical and Applied …, 2021 - journals.sagepub.com
The complex pathophysiology of pulmonary embolism (PE) involves hemostatic activation,
inflammatory processes, cellular dysfunction, and hemodynamic derangements. Due to the …

Platelet-to-lymphocyte ratio as a novel marker of in-hospital and long-term adverse outcomes among patients with acute pulmonary embolism: A single center large …

EHO Cetin, MS Cetin, U Canpolat, A Akdi, D Aras… - Thrombosis research, 2017 - Elsevier
Background The interaction of platelets with leukocytes is a well-known process both in
progression and prognosis of acute pulmonary embolism (PE). Recently, platelet to …

The prognostic importance of thiol/disulfide homeostasis in patients with acute pulmonary thromboembolism

M Topuz, M Kaplan, O Akkus, O Sen, HD Yunsel… - The American journal of …, 2016 - Elsevier
Objective The aim of this study was to evaluate the role of thiol/disulfide homeostasis in
acute pulmonary embolism (APE) and investigate its compliance to show hospital mortality …

Metabolic landscape in venous thrombosis: insights into molecular biology and therapeutic implications

Z Cao, X Jiang, Y He, X Zheng - Annals of Medicine, 2024 - Taylor & Francis
The findings of the last decade suggest a complex link between inflammatory cells,
coagulation, and the activation of platelets and their synergistic interaction to promote …

Platelet hyperactivation, apoptosis and hypercoagulability in patients with acute pulmonary embolism

S Rezania, MA Puskarich, DN Petrusca… - Thrombosis research, 2017 - Elsevier
Abstract Changes in systemic redox balance can alter platelet activation and aggregation.
Acute pulmonary embolism (PE) is a systematic inflammatory disease associated with …

Endothelial PTP1B Deletion Promotes VWF Exocytosis and Venous Thromboinflammation

K Zifkos, ML Bochenek, R Gogiraju, S Robert… - Circulation …, 2024 - Am Heart Assoc
BACKGROUND: Endothelial activation promotes the release of procoagulant extracellular
vesicles and inflammatory mediators from specialized storage granules. Endothelial …

Importance of oxidative stress in the evaluation of acute pulmonary embolism severity

G Sagcan, D Konukoglu, H Uzun, O Arseven… - BMC Pulmonary …, 2022 - Springer
Background Pulmonary embolism (PE) is a common and potentially life-threatening
disorder. Our study was aimed to investigate whether oxidative stress markers can be used …

Comparison of acute and convalescent biomarkers of inflammation in patients with acute pulmonary embolism treated with systemic fibrinolysis vs. placebo

LK Stewart, KE Nordenholz, M Courtney… - Blood Coagulation & …, 2017 - journals.lww.com
Previous studies have associated biomarkers indicative of acute inflammation with
pulmonary embolism, which may amplify coagulation, inhibit fibrinolysis and increase risk of …