Global epidemiology of cirrhosis—aetiology, trends and predictions

DQ Huang, NA Terrault, F Tacke, LL Gluud… - Nature reviews …, 2023 - nature.com
Cirrhosis is an important cause of morbidity and mortality in people with chronic liver
disease worldwide. In 2019, cirrhosis was associated with 2.4% of global deaths. Owing to …

Evidence-based clinical practice guidelines for Liver Cirrhosis 2020

H Yoshiji, S Nagoshi, T Akahane, Y Asaoka… - Journal of …, 2021 - Springer
The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010,
and the second edition was published in 2015 by the Japanese Society of Gastroenterology …

Mechanisms of hepatic stellate cell activation

T Tsuchida, SL Friedman - Nature reviews Gastroenterology & …, 2017 - nature.com
Hepatic fibrosis is a dynamic process characterized by the net accumulation of extracellular
matrix resulting from chronic liver injury of any aetiology, including viral infection, alcoholic …

Mechanisms of liver fibrosis and its role in liver cancer

D Dhar, J Baglieri, T Kisseleva… - … Biology and Medicine, 2020 - journals.sagepub.com
Hepatic fibrogenesis is a pathophysiological outcome of chronic liver injury hallmarked by
excessive accumulation of extracellular matrix proteins. Fibrosis is a dynamic process that …

Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update

SK Sarin, M Kumar, GK Lau, Z Abbas, HLY Chan… - Hepatology …, 2016 - Springer
Worldwide, some 240 million people have chronic hepatitis B virus (HBV), with the highest
rates of infection in Africa and Asia. Our understanding of the natural history of HBV infection …

[PDF][PDF] A ASLD guidelines for treatment of chronic hepatitis B

NA Terrault, NH Bzowej, KM Chang, JP Hwang… - …, 2016 - Wiley Online Library
A<fc>ASLD</fc> guidelines for treatment of chronic hepatitis <fc>B</fc> Page 1 PRACTICE
GUIDELINE AASLD Guidelines for Treatment of Chronic Hepatitis B Norah A. Terrault,1 Natalie …

Off-therapy response after nucleos (t) ide analogue withdrawal in patients with chronic hepatitis B: an international, multicenter, multiethnic cohort (RETRACT-B study)

G Hirode, HSJ Choi, CH Chen, TH Su, WK Seto… - Gastroenterology, 2022 - Elsevier
Background & Aims Functional cure, defined based on hepatitis B surface antigen (HBsAg)
loss, is rare during nucleos (t) ide analogue (NA) therapy and guidelines on finite NA …

[HTML][HTML] Limitations of non-invasive tests for assessment of liver fibrosis

K Patel, G Sebastiani - JHEP Reports, 2020 - Elsevier
The diagnostic assessment of liver injury is an important step in the management of patients
with chronic liver disease (CLD). Although liver biopsy is the reference standard for the …

Hepatitis B virus infection

C Trépo, HLY Chan, A Lok - The Lancet, 2014 - thelancet.com
Hepatitis B virus infection is a major public health problem worldwide; roughly 30% of the
world's population show serological evidence of current or past infection. Hepatitis B virus is …

AASLD Practice Guideline on blood-based noninvasive liver disease assessment of hepatic fibrosis and steatosis

RK Sterling, K Patel, A Duarte-Rojo, SK Asrani… - Hepatology, 2025 - journals.lww.com
Chronic liver disease (CLD) leads to liver fibrosis; it is associated with approximately two
million annual deaths worldwide and is an enormous health burden.[1, 2] The majority of …