The complexity of host–pathogen interactions often leads to distinct clinical outcomes upon
infection with different pathogen strains. In this Review, we explore the interactions between …

Chagas disease, a neglected tropical disease present in the Americas, is caused by the
parasite Trypanosoma cruzi and is transmitted by triatomine kissing bug vectors. Hundreds …

Trypanosoma cruzi (T. cruzi) is the causative agent for Chagas disease (CD). There is a
critical lack of methods for prevention of infection or treatment of acute infection and chronic …

An estimated 7–8 million people are infected worldwide with almost all of the cases
occurring in the Americas, predominantly in the poorest countries in the region [2–4] …

Chagas disease (CD) is a vector-borne Neglected Zoonotic Disease (NZD) caused by a
flagellate protozoan, Trypanosoma cruzi, that affects various mammalian species across …

Chagas disease is a major neglected tropical disease, transmitted predominantly by
triatomine insect vectors, but also through congenital and oral routes. While endemic in the …

Trypanos o ma cruzi (T. cruzi or Tc) is the causative agent of Chagas disease (CD). It is
common for patients to suffer from non-specific symptoms or be clinically asymptomatic with …

Herpes viruses are responsible for a variety of pathological effects in humans and in both
wild and domestic animals. One mechanism that has been proposed to facilitate replication …

The development of suitable safe adjuvants to enhance appropriate antigen-driven immune
responses remains a challenge. Here we describe the adjuvant properties of a small …

The present work aimed to review the immune response from different triatomines against
Trypanosoma cruzi and Trypanosoma rangeli and propose the study of immune memory in …