[HTML][HTML] Pathogen diversity, immunity, and the fate of infections: lessons learned from Trypanosoma cruzi human–host interactions
LMD Magalhães, KJ Gollob, B Zingales… - The Lancet …, 2022 - thelancet.com
The complexity of host–pathogen interactions often leads to distinct clinical outcomes upon
infection with different pathogen strains. In this Review, we explore the interactions between …
infection with different pathogen strains. In this Review, we explore the interactions between …
Chagas Disease Ecology in the United States: Recent Advances in Understanding Trypanosoma cruzi Transmission Among Triatomines, Wildlife, and Domestic …
RE Busselman, SA Hamer - Annual review of animal …, 2022 - annualreviews.org
Chagas disease, a neglected tropical disease present in the Americas, is caused by the
parasite Trypanosoma cruzi and is transmitted by triatomine kissing bug vectors. Hundreds …
parasite Trypanosoma cruzi and is transmitted by triatomine kissing bug vectors. Hundreds …
[HTML][HTML] Immunity and vaccine development efforts against Trypanosoma cruzi
Trypanosoma cruzi (T. cruzi) is the causative agent for Chagas disease (CD). There is a
critical lack of methods for prevention of infection or treatment of acute infection and chronic …
critical lack of methods for prevention of infection or treatment of acute infection and chronic …
[PDF][PDF] Status of vaccine research and development of vaccines for Chagas disease
CM Beaumier, PM Gillespie, U Strych, T Hayward… - Vaccine, 2016 - core.ac.uk
An estimated 7–8 million people are infected worldwide with almost all of the cases
occurring in the Americas, predominantly in the poorest countries in the region [2–4] …
occurring in the Americas, predominantly in the poorest countries in the region [2–4] …
[HTML][HTML] Chagas disease: a silent threat for dogs and humans
J Durães-Oliveira, J Palma-Marques, C Moreno… - International Journal of …, 2024 - mdpi.com
Chagas disease (CD) is a vector-borne Neglected Zoonotic Disease (NZD) caused by a
flagellate protozoan, Trypanosoma cruzi, that affects various mammalian species across …
flagellate protozoan, Trypanosoma cruzi, that affects various mammalian species across …
[HTML][HTML] The case for the development of a Chagas disease vaccine: why? How? When?
E Dumonteil, C Herrera - Tropical Medicine and Infectious Disease, 2021 - mdpi.com
Chagas disease is a major neglected tropical disease, transmitted predominantly by
triatomine insect vectors, but also through congenital and oral routes. While endemic in the …
triatomine insect vectors, but also through congenital and oral routes. While endemic in the …
[HTML][HTML] Epidemiology and pathogenesis of maternal-fetal transmission of Trypanosoma cruzi and a case for vaccine development against congenital Chagas disease
Trypanos o ma cruzi (T. cruzi or Tc) is the causative agent of Chagas disease (CD). It is
common for patients to suffer from non-specific symptoms or be clinically asymptomatic with …
common for patients to suffer from non-specific symptoms or be clinically asymptomatic with …
Oxidative stress favours herpes virus infection in vertebrates: a meta-analysis
Herpes viruses are responsible for a variety of pathological effects in humans and in both
wild and domestic animals. One mechanism that has been proposed to facilitate replication …
wild and domestic animals. One mechanism that has been proposed to facilitate replication …
[HTML][HTML] Use of a small molecule integrin activator as a systemically administered vaccine adjuvant in controlling Chagas disease
N Lokugamage, IH Chowdhury, RJ Biediger… - npj Vaccines, 2021 - nature.com
The development of suitable safe adjuvants to enhance appropriate antigen-driven immune
responses remains a challenge. Here we describe the adjuvant properties of a small …
responses remains a challenge. Here we describe the adjuvant properties of a small …
The innate immune response of triatomines against Trypanosoma cruzi and Trypanosoma rangeli with an unresolved question: Do triatomines have immune memory?
SP Carmona-Peña, J Contreras-Garduño, DP Castro… - Acta Tropica, 2021 - Elsevier
The present work aimed to review the immune response from different triatomines against
Trypanosoma cruzi and Trypanosoma rangeli and propose the study of immune memory in …
Trypanosoma cruzi and Trypanosoma rangeli and propose the study of immune memory in …