Reporting recommendations for tumor marker prognostic studies (REMARK): an abridged explanation and elaboration

W Sauerbrei, SE Taube, LM McShane… - JNCI: Journal of the …, 2018 - academic.oup.com
Abstract The Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK)
were developed to address widespread deficiencies in the reporting of such studies. The …

Role of blood-based biomarkers in ischemic stroke prognosis: a systematic review

FA Montellano, K Ungethüm, L Ramiro, A Nacu… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Outcome prognostication in ischemic stroke patients remains
challenging due to limited predictive properties of existing models. Blood-based biomarkers …

Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration

DG Altman, LM McShane, W Sauerbrei, SE Taube - BMC medicine, 2012 - Springer
Abstract Background The Reporting Recommendations for Tumor Marker Prognostic
Studies (REMARK) checklist consists of 20 items to report for published tumor marker …

Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis

P Deb, S Sharma, KM Hassan - Pathophysiology, 2010 - Elsevier
Stroke is a serious neurological disease, and constitutes a major cause of death and
disability throughout the world. The pathophysiology of stroke is complex, and involves …

Acute stroke biomarkers: are we there yet?

M Dagonnier, GA Donnan, SM Davis… - Frontiers in …, 2021 - frontiersin.org
Background: Distinguishing between stroke subtypes and knowing the time of stroke onset
are critical in clinical practice. Thrombolysis and thrombectomy are very effective treatments …

Stroke rehabilitation: recent advances and future therapies

L Brewer, F Horgan, A Hickey… - QJM: An International …, 2013 - academic.oup.com
Despite advances in the acute management of stroke, a large proportion of stroke patients
are left with significant impairments. Over the coming decades the prevalence of stroke …

Blood biomarkers for stroke diagnosis and management

J Kamtchum-Tatuene, GC Jickling - Neuromolecular medicine, 2019 - Springer
Biomarkers are objective indicators used to assess normal or pathological processes,
evaluate responses to treatment and predict outcomes. Many blood biomarkers already …

Stroke biomarkers: progress and challenges for diagnosis, prognosis, differentiation, and treatment

AK Saenger, RH Christenson - Clinical chemistry, 2010 - academic.oup.com
Background: Stroke is a devastating condition encompassing a wide range of
pathophysiological entities that include thrombosis, hemorrhage, and embolism. Current …

[PDF][PDF] The stress hormone copeptin: a new prognostic biomarker in acute illness

M Christ-Crain - Swiss medical weekly, 2010 - smw.ch
Stress is defined as anything that throws the body out of homeostatic balance; for example
an acute illness. Any stressor which activates the hypothalamo-pituitary-adrenal (HPA) axis …

Inflammatory markers and poor outcome after stroke: a prospective cohort study and systematic review of interleukin-6

W Whiteley, C Jackson, S Lewis, G Lowe… - PLoS …, 2009 - journals.plos.org
Background The objective of this study was to determine whether:(a) markers of acute
inflammation (white cell count, glucose, interleukin-6, C-reactive protein, and fibrinogen) are …