[HTML][HTML] The origins and potential future of SARS-CoV-2 variants of concern in the evolving COVID-19 pandemic

SP Otto, T Day, J Arino, C Colijn, J Dushoff, M Li… - Current Biology, 2021 - Elsevier
One year into the global COVID-19 pandemic, the focus of attention has shifted to the
emergence and spread of SARS-CoV-2 variants of concern (VOCs). After nearly a year of …

[HTML][HTML] Animal models for COVID-19

C Muñoz-Fontela, WE Dowling, SGP Funnell, PS Gsell… - Nature, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological agent of
coronavirus disease 2019 (COVID-19), an emerging respiratory infection caused by the …

[HTML][HTML] SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters

PJ Halfmann, S Iida, K Iwatsuki-Horimoto, T Maemura… - Nature, 2022 - nature.com
The recent emergence of B. 1.1. 529, the Omicron variant,, has raised concerns of escape
from protection by vaccines and therapeutic antibodies. A key test for potential …

[HTML][HTML] SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity

C Motozono, M Toyoda, J Zahradnik, A Saito… - Cell host & …, 2021 - Elsevier
Many SARS-CoV-2 variants with naturally acquired mutations have emerged. These
mutations can affect viral properties such as infectivity and immune resistance. Although the …

[HTML][HTML] SARS-CoV-2 infection in free-ranging white-tailed deer

VL Hale, PM Dennis, DS McBride, JM Nolting… - Nature, 2022 - nature.com
Humans have infected a wide range of animals with SARS-CoV-2–, but the establishment of
a new natural animal reservoir has not been observed. Here we document that free-ranging …

[HTML][HTML] Bat coronaviruses related to SARS-CoV-2 and infectious for human cells

S Temmam, K Vongphayloth, E Baquero, S Munier… - Nature, 2022 - nature.com
The animal reservoir of SARS-CoV-2 is unknown despite reports of SARS-CoV-2-related
viruses in Asian Rhinolophus bats–, including the closest virus from R. affinis, RaTG13 …

SARS-CoV-2 exposure in wild white-tailed deer (Odocoileus virginianus)

JC Chandler, SN Bevins, JW Ellis… - Proceedings of the …, 2021 - National Acad Sciences
Widespread human SARS-CoV-2 infections combined with human–wildlife interactions
create the potential for reverse zoonosis from humans to wildlife. We targeted white-tailed …

Multiple spillovers from humans and onward transmission of SARS-CoV-2 in white-tailed deer

SV Kuchipudi, M Surendran-Nair… - Proceedings of the …, 2022 - National Acad Sciences
Many animal species are susceptible to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection and could act as reservoirs; however, transmission in free-living …

Mutations on RBD of SARS-CoV-2 Omicron variant result in stronger binding to human ACE2 receptor

CS Lupala, Y Ye, H Chen, XD Su, H Liu - Biochemical and biophysical …, 2022 - Elsevier
The COVID-19 pandemic caused by the SARS-CoV-2 virus has led to more than 270 million
infections and 5.3 million of deaths worldwide. Several major variants of SARS-CoV-2 have …

[HTML][HTML] On the origin and evolution of SARS-CoV-2

D Singh, SV Yi - Experimental & Molecular Medicine, 2021 - nature.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
ongoing global outbreak of a coronavirus disease (herein referred to as COVID-19). Other …