Despite the significant progress in the fields of biology, physiology, molecular medicine, and
pharmacology; the designation of the properties of nitrogen monoxide in the regulation of life …

The p-aminobenzoic acid was applied for the synthesis of substituted 1-phenyl-5-
oxopyrrolidine derivatives containing benzimidazole, azole, oxadiazole, triazole …

Herein we report an annulation of phenylhydrazone via a tandem nitrification, reduction,
cyclization protocol employing cobalt nitrate and 1, 2‐dichloroethane to produce substituted …

Objectives: Periodontal diseases are a rather complex problem of modern dentistry and do
not have only medical but also social significance. The objective of this study is to weigh the …

Herein, we presented a review to show that the main mechanism underlying endothelial
dysfunction is a decrease in the formation and bioavailability of NO against the background …

Numerous studies on the effects of antihypertensive treatment in young spontaneously
hypertensive rats (SHRs) have shown that early-onset therapy may effectively reduce their …

Bromide 1-(β-phenylethyl)-4-amino-1, 2, 4-triazolium (Hypertril) has the properties of a beta-
blocker and of NO-mimetic, is assigned to the IV class of toxicity. All these effects make …

In the complex treatment of chronic heart failure (CHF) β-adrenoblockers (carvedilol,
nebivolol, bisoprolol, metoprolol) are used, which due to their pharmacological properties …

Spontaneously hypertensive rats (SHR) are an established animal model for
antihypertensive treatment. The aim of this pilot study was a systematic search for two lines …

Aim. The purpose of this study was to conduct an up-to-date semantic analysis of the results
of our own research and literature data on the medical and pharmacological characteristics …