The induction and action of type I interferon (IFN) is of fundamental importance in human
immune defenses toward microbial pathogens, particularly viruses. Basic discoveries within …

We report the updated classification of Inborn Errors of Immunity/Primary
Immunodeficiencies, compiled by the International Union of Immunological Societies Expert …

Coronavirus disease-19 (COVID-19) describes a set of symptoms that develop following
infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Whilst …

COVID-19 has caused numerous infections with diverse clinical symptoms. To identify
human genetic variants contributing to the clinical development of COVID-19, we genotyped …

The field of Immunology is one that has undergone great expansion in recent years. With the
advent of new diagnostic modalities including a variety of genetic tests (discussed …

Until now, relatively little is known about marine-derived fungal polysaccharides and their
activities. Exopolysaccharide AVP141-A was isolated from the broth of marine-derived …

Predominantly antibody deficiency (PAD) is the most prevalent form of primary
immunodeficiency, and is characterized by broad clinical, immunological and genetic …

Since the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2)/coronavirus disease 2019 (COVID-19) pandemic, global sequencing efforts have led in …

ACAA are an emerging cause of acquired immunodeficiency which is likely
underdiagnosed. Recent case reports document expanding spectra of clinical …

Highlights•Human inborn errors of innate immunity can present as increased susceptibility to
infection with a narrow range of pathogens.•Non-hematopoietic tissue resident cells play a …