The SOFA score—development, utility and challenges of accurate assessment in clinical trials

S Lambden, PF Laterre, MM Levy, B Francois - Critical Care, 2019 - Springer
Abstract The Sequential Organ Failure Assessment or SOFA score was developed to assess
the acute morbidity of critical illness at a population level and has been widely validated as a …

Sepsis and septic shock

M Cecconi, L Evans, M Levy, A Rhodes - The Lancet, 2018 - thelancet.com
Sepsis is a common condition that is associated with unacceptably high mortality and, for
many of those who survive, long-term morbidity. Increased awareness of the condition …

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

L Evans, A Rhodes, W Alhazzani, M Antonelli… - Critical care …, 2021 - journals.lww.com
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

European Resuscitation Council Guidelines 2021: cardiac arrest in special circumstances

C Lott, A Truhlář, A Alfonzo, A Barelli… - Resuscitation, 2021 - Elsevier
Abstract These European Resuscitation Council (ERC) Cardiac Arrest in Special
Circumstances guidelines are based on the 2020 International Consensus on …

Caring for critically ill patients with the ABCDEF bundle: results of the ICU liberation collaborative in over 15,000 adults

BT Pun, MC Balas, MA Barnes-Daly… - Critical care …, 2019 - journals.lww.com
Objective: Decades-old, common ICU practices including deep sedation, immobilization,
and limited family access are being challenged. We endeavoured to evaluate the …

Prevalence, underlying causes, and preventability of sepsis-associated mortality in US acute care hospitals

C Rhee, TM Jones, Y Hamad, A Pande… - JAMA network …, 2019 - jamanetwork.com
Importance Sepsis is present in many hospitalizations that culminate in death. The
contribution of sepsis to these deaths, and the extent to which they are preventable, is …

Frequency and mortality of septic shock in Europe and North America: a systematic review and meta-analysis

JL Vincent, G Jones, S David, E Olariu, KK Cadwell - Critical care, 2019 - Springer
Background Septic shock is the most severe form of sepsis, in which profound underlying
abnormalities in circulatory and cellular/metabolic parameters lead to substantially …

The third international consensus definitions for sepsis and septic shock (Sepsis-3)

M Singer, CS Deutschman, CW Seymour… - Jama, 2016 - jamanetwork.com
Importance Definitions of sepsis and septic shock were last revised in 2001. Considerable
advances have since been made into the pathobiology (changes in organ function …

Developing a new definition and assessing new clinical criteria for septic shock: for the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis …

M Shankar-Hari, GS Phillips, ML Levy, CW Seymour… - Jama, 2016 - jamanetwork.com
Importance Septic shock currently refers to a state of acute circulatory failure associated with
infection. Emerging biological insights and reported variation in epidemiology challenge the …

Epidemiology of sepsis and septic shock

C Chiu, M Legrand - Current Opinion in Anesthesiology, 2021 - journals.lww.com
Epidemiology of sepsis and septic shock : Current Opinion in Anesthesiology Epidemiology of
sepsis and septic shock : Current Opinion in Anesthesiology Log in or Register Subscribe to …