[HTML][HTML] Long non-coding RNAs: from disease code to drug role
Y Chen, Z Li, X Chen, S Zhang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Enormous studies have corroborated that long non-coding RNAs (lncRNAs) extensively
participate in crucial physiological processes such as metabolism and immunity, and are …
participate in crucial physiological processes such as metabolism and immunity, and are …
Role of long non-coding RNAs in pancreatic cancer pathogenesis and treatment resistance-A review
Pancreatic cancer (PC) is one of the deadliest cancers associated with poor prognosis. The
lack of reliable means of early cancer detection contributes to this disease's dismal …
lack of reliable means of early cancer detection contributes to this disease's dismal …
Non-coding RNA in cancer drug resistance: Underlying mechanisms and clinical applications
X Zhou, X Ao, Z Jia, Y Li, S Kuang, C Du… - Frontiers in …, 2022 - frontiersin.org
Cancer is one of the most frequently diagnosed malignant diseases worldwide, posing a
serious, long-term threat to patients' health and life. Systemic chemotherapy remains the first …
serious, long-term threat to patients' health and life. Systemic chemotherapy remains the first …
Small molecule recognition of disease-relevant RNA structures
SM Meyer, CC Williams, Y Akahori, T Tanaka… - Chemical Society …, 2020 - pubs.rsc.org
Targeting RNAs with small molecules represents a new frontier in drug discovery and
development. The rich structural diversity of folded RNAs offers a nearly unlimited reservoir …
development. The rich structural diversity of folded RNAs offers a nearly unlimited reservoir …
[HTML][HTML] LncRNA H19: A novel oncogene in multiple cancers
J Yang, M Qi, X Fei, X Wang, K Wang - International journal of …, 2021 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) are a series of non-coding RNAs that lack open reading
frameworks. Accumulating evidence suggests important roles for lncRNAs in various …
frameworks. Accumulating evidence suggests important roles for lncRNAs in various …
Insights on the potential oncogenic impact of long non-coding RNA nicotinamide nucleotide transhydrogenase antisense RNA 1 in different cancer types; integrating …
NM El-Sheikh, AI Abulsoud, EF Wasfey… - Pathology-Research and …, 2022 - Elsevier
Long non-coding RNAs (lncRNAs) are becoming more prevalent in the cancer field arena,
with functional roles in both oncogenic and onco-suppressive pathways. Despite their …
with functional roles in both oncogenic and onco-suppressive pathways. Despite their …
Long non-coding RNAs and microRNAs interplay in osteogenic differentiation of mesenchymal stem cells
C Lanzillotti, M De Mattei, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
Long non-coding RNAs (lncRNAs) have gained great attention as epigenetic regulators of
gene expression in many tissues. Increasing evidence indicates that lncRNAs, together with …
gene expression in many tissues. Increasing evidence indicates that lncRNAs, together with …
Epigenetics in Alzheimer's disease
X Gao, Q Chen, H Yao, J Tan, Z Liu, Y Zhou… - Frontiers in aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disease with unknown pathogenesis and
complex pathological manifestations. At present, a large number of studies on targeted …
complex pathological manifestations. At present, a large number of studies on targeted …
Long non-coding RNA (lncRNA) roles in cell biology, neurodevelopment and neurological disorders
V Aliperti, J Skonieczna, A Cerase - Non-coding RNA, 2021 - mdpi.com
Development is a complex process regulated both by genetic and epigenetic and
environmental clues. Recently, long non-coding RNAs (lncRNAs) have emerged as key …
environmental clues. Recently, long non-coding RNAs (lncRNAs) have emerged as key …
Competing endogenous RNAs, non-coding RNAs and diseases: an intertwined story
U Ala - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs), a class of small non-coding RNA molecules, are responsible for RNA
silencing and post-transcriptional regulation of gene expression. They can mediate a fine …
silencing and post-transcriptional regulation of gene expression. They can mediate a fine …