External validity
External validity captures the extent to which inferences drawn from a given study's sample
apply to a broader population or other target populations. Social scientists frequently invoke …
apply to a broader population or other target populations. Social scientists frequently invoke …
Designing difference in difference studies: best practices for public health policy research
The difference in difference (DID) design is a quasi-experimental research design that
researchers often use to study causal relationships in public health settings where …
researchers often use to study causal relationships in public health settings where …
Post-2020 biodiversity framework challenged by cropland expansion in protected areas
Protected areas (PAs) are essential for biodiversity conservation but are threatened by
cropland expansion. Recent studies have only reported global cropland expansion in large …
cropland expansion. Recent studies have only reported global cropland expansion in large …
[PDF][PDF] Association of blood glucose control and outcomes in patients with COVID-19 and pre-existing type 2 diabetes
Summary Type 2 diabetes (T2D) is a major comorbidity of COVID-19. However, the impact of
blood glucose (BG) control on the degree of required medical interventions and on mortality …
blood glucose (BG) control on the degree of required medical interventions and on mortality …
Tocilizumab among patients with COVID-19 in the intensive care unit: a multicentre observational study
Background Tocilizumab, a monoclonal antibody directed against the interleukin-6 receptor,
has been proposed to mitigate the cytokine storm syndrome associated with severe COVID …
has been proposed to mitigate the cytokine storm syndrome associated with severe COVID …
Real-world use of nirmatrelvir–ritonavir in outpatients with COVID-19 during the era of omicron variants including BA. 4 and BA. 5 in Colorado, USA: a retrospective …
NR Aggarwal, KC Molina, LE Beaty… - The Lancet Infectious …, 2023 - thelancet.com
Background Nirmatrelvir is a protease inhibitor with in-vitro activity against SARS-CoV-2,
and ritonavir-boosted nirmatrelvir can reduce the risk of progression to severe COVID-19 …
and ritonavir-boosted nirmatrelvir can reduce the risk of progression to severe COVID-19 …
The mental health of frontline and non-frontline medical workers during the coronavirus disease 2019 (COVID-19) outbreak in China: A case-control study
Q Cai, H Feng, J Huang, M Wang, Q Wang, X Lu… - Journal of affective …, 2020 - Elsevier
Background and objective Coronavirus disease 2019 (COVID-19) is a new infectious
disease with high transmissibility and morbidity. It has caused substantial mental distress to …
disease with high transmissibility and morbidity. It has caused substantial mental distress to …
[PDF][PDF] The polygenic and monogenic basis of blood traits and diseases
Blood cells play essential roles in human health, underpinning physiological processes
such as immunity, oxygen transport, and clotting, which when perturbed cause a significant …
such as immunity, oxygen transport, and clotting, which when perturbed cause a significant …
JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality
J Stebbing, G Sánchez Nievas, M Falcone… - Science …, 2021 - science.org
Using AI, we identified baricitinib as having antiviral and anticytokine efficacy. We now show
a 71%(95% CI 0.15 to 0.58) mortality benefit in 83 patients with moderate-severe SARS-CoV …
a 71%(95% CI 0.15 to 0.58) mortality benefit in 83 patients with moderate-severe SARS-CoV …
[HTML][HTML] Balance diagnostics after propensity score matching
Propensity score matching (PSM) is a popular method in clinical researches to create a
balanced covariate distribution between treated and untreated groups. However, the …
balanced covariate distribution between treated and untreated groups. However, the …