Development of in vitro 2D and 3D microelectrode arrays and their role in advancing biomedical research

CM Didier, A Kundu, D DeRoo… - … of Micromechanics and …, 2020 - iopscience.iop.org
The development of microelectrode arrays (MEAs) along with complementary advances in
electronics, mechanics and software to connect with these arrays has led to the in vitro …

Enhanced Electrochemical Impedance Spectroscopy Analysis of Microbial Biofilms on an Electrochemically In Situ Generated Graphene Interface

J Song, Y Li, F Yin, Z Zhang, D Ke, D Wang, Q Yuan… - ACS …, 2020 - ACS Publications
Biofilms can cause many bacterial diseases, such as dental disease. An in vitro detection of
biofilms may help to screen antibiofilm drugs. An impedance measurement based on an Au …

Small‐Scale Biological and Artificial Multidimensional Sensors for 3D Sensing

K Agarwal, S Hwang, A Bartnik, N Buchele, A Mishra… - Small, 2018 - Wiley Online Library
A vast majority of existing sub‐millimeter‐scale sensors have a planar, 2D geometry as a
result of conventional top‐down lithographic procedures. However, 2D sensors often suffer …

Carbon nanotubes, directly grown on supporting surfaces, improve neuronal activity in hippocampal neuronal networks

I Rago, R Rauti, M Bevilacqua, I Calaresu… - Advanced …, 2019 - Wiley Online Library
Carbon nanotube (CNT)–modified surfaces unequivocally demonstrate their biocompatibility
and ability to boost the electrical activity of neuronal cells cultured on them. Reasons for this …

A novel 3D helical microelectrode array for in vitro extracellular action potential recording

N Geramifard, J Lawson, SF Cogan, BJ Black - Micromachines, 2022 - mdpi.com
Recent advances in cell and tissue engineering have enabled long-term three-dimensional
(3D) in vitro cultures of human-derived neuronal tissues. Analogous two-dimensional (2D) …

A multiwell plate Organ-on-Chip (OOC) device for in-vitro cell culture stimulation and monitoring

N Gaio, A Waafi, MLH Vlaming… - 2018 IEEE Micro …, 2018 - ieeexplore.ieee.org
This work presents the first multi-well plate that allows for simultaneous mechanical
stimulation and electrical monitoring of multiple in-vitro cell cultures in parallel. Each well of …

Technology development for MEMS: A tutorial

PJ French, GJM Krijnen, S Vollebregt… - IEEE Sensors …, 2021 - ieeexplore.ieee.org
Silicon sensors date back to before 1960 with early Hall and piezoresistive devices. These
used simple processing that was part of the early integrated circuit (IC) industry. As the IC …

Semitransparent carbon microelectrodes for opto-and electrophysiology

P Kshirsagar, M Martina, PD Jones… - Journal of …, 2018 - iopscience.iop.org
Transparent microelectrodes can enable electrophysiology with simultaneous optical
stimulation or imaging directly at the electrode site. Owing to their high surface area …

2D and 3D Models of Acute and Chronic Nociception Using Human Induced Pluripotent Stem Cell Sensory Cultures on Multi-Well Microelectrode Arrays

JM Lawson - 2022 - search.proquest.com
Chronic pain is the US's# 1 public health crisis: with high incidence and no viable treatment
options. Existing pain management options based on pharmaceutical drugs lead to …

Prediction models for hyperglycemia effect duration of cardiac conduction systems using sinoatrial node field potential

F Yu - 2018 Chinese Control And Decision Conference …, 2018 - ieeexplore.ieee.org
Sinoatrial node field potential is an important electrophysiological signal in cardiac
conduction systems. The field potential is highly sensitive to high glucose. With the different …