A systematic review and synthesis of global stroke guidelines on behalf of the World Stroke Organization

GE Mead, LA Sposato… - … Journal of Stroke, 2023 - journals.sagepub.com
Background: There are multiple stroke guidelines globally. To synthesize these and
summarize what existing stroke guidelines recommend about the management of people …

Canadian stroke best practice recommendations: acute stroke management, practice guidelines update, 2022

M Heran, P Lindsay, G Gubitz, A Yu… - Canadian Journal of …, 2024 - cambridge.org
The 2022 update of the Canadian Stroke Best Practice Recommendations (CSBPR) for
Acute Stroke Management, 7th edition, is a comprehensive summary of current evidence …

Factor XIa inhibition with asundexian after acute non-cardioembolic ischaemic stroke (PACIFIC-Stroke): an international, randomised, double-blind, placebo …

A Shoamanesh, H Mundl, EE Smith, J Masjuan… - The Lancet, 2022 - thelancet.com
Summary Background Asundexian (Bayer AG, Leverkusen, Germany), an oral small
molecule factor XIa (FXIa) inhibitor, might prevent thrombosis without increasing bleeding …

Benefits of GLP-1 (glucagon-like peptide 1) receptor agonists for stroke reduction in type 2 diabetes: a call to action for neurologists

RM Goldenberg, AYY Cheng, T Fitzpatrick, JD Gilbert… - Stroke, 2022 - Am Heart Assoc
People living with diabetes are at higher risk for stroke and have a poorer prognosis
following a stroke event than those without diabetes. Data from cardiovascular outcome …

Determinants and temporal trends of dual antiplatelet therapy after mild noncardioembolic stroke

VJ Del Brutto, R Yin, H Gardener, H Ying, CM Gutierrez… - Stroke, 2023 - Am Heart Assoc
BACKGROUND: Short-term dual antiplatelet therapy (DAPT) reduces early stroke
recurrence after mild noncardioembolic ischemic stroke (NCIS). We aim to evaluate …

Atrial fibrillation detection and load: knowledge gaps related to stroke prevention

EE Smith, S Yaghi, LA Sposato, M Fisher - Stroke, 2024 - Am Heart Assoc
Atrial fibrillation is a major cause of ischemic stroke. Technological advances now support
prolonged cardiac rhythm monitoring using either surface electrodes or insertable cardiac …

GLP-1 receptor agonists and risk of adverse cerebrovascular outcomes in type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials

M Banerjee, R Pal, S Mukhopadhyay… - The Journal of Clinical …, 2023 - academic.oup.com
Context The effect of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on
ischemic/hemorrhagic stroke and transient ischemic attacks (TIA) in type 2 diabetes mellitus …

Divergence between clinical trial evidence and actual practice in use of dual antiplatelet therapy after transient ischemic attack and minor stroke

E De Matteis, F De Santis, R Ornello, B Censori… - Stroke, 2023 - Am Heart Assoc
Background: Randomized controlled trials (RCTs) proved that short-term (21–90 days) dual
antiplatelet therapy (DAPT) reduces the risk of early ischemic recurrences after a …

Aetiology of extracranial carotid free-floating thrombus in a prospective multicentre cohort

D Dowlatshahi, C Lum, BK Menon… - Stroke and Vascular …, 2023 - svn.bmj.com
Background Carotid free-floating thrombi (FFT) in patients with acute transient ischaemic
attack (TIA)/stroke have a high risk of early recurrent stroke. Management depends on …

[HTML][HTML] Impact of CYP2C19 genotype on efficacy and safety of Clopidogrel-based antiplatelet therapy in stroke or transient ischemic attack patients: an updated …

S Cargnin, F Ferrari, S Terrazzino - Cardiovascular Drugs and Therapy, 2023 - Springer
Purpose Inconclusive and limited results have been reported on the clinical utility of
CYP2C19 genotyping in stroke/TIA patients of non-East Asian ancestries. We herein …