Stochastic sensing of dynamic interactions and chemical reactions with nanopores/nanochannels

X Zhang, M Lin, Y Dai, F Xia - Analytical Chemistry, 2023 - ACS Publications
Nanopore sensing technology is an emerging analysis method with the advantages of
simple operation, high sensitivity, fast output and being label free, and it is widely used in …

Solid-state and polymer nanopores for protein sensing: A review

N Meyer, I Abrao-Nemeir, JM Janot, J Torrent… - Advances in colloid and …, 2021 - Elsevier
In two decades, the solid state and polymer nanopores became attractive method for the
protein sensing with high specificity and sensitivity. They also allow the characterization of …

DNA nanotechnology assisted nanopore-based analysis

T Ding, J Yang, V Pan, N Zhao, Z Lu, Y Ke… - Nucleic acids …, 2020 - academic.oup.com
Nanopore technology is a promising label-free detection method. However, challenges exist
for its further application in sequencing, clinical diagnostics and ultra-sensitive single …

Circulating tumor cells in cancer diagnostics and prognostics by single-molecule and single-cell characterization

T Chowdhury, B Cressiot, C Parisi, G Smolyakov… - ACS …, 2023 - ACS Publications
Circulating tumor cells (CTCs) represent an interesting source of biomarkers for diagnosis,
prognosis, and the prediction of cancer recurrence, yet while they are extensively studied in …

DNA sequencing: an overview of solid-state and biological nanopore-based methods

MM Mohammadi, O Bavi - Biophysical reviews, 2022 - Springer
The field of sequencing is a topic of significant interest since its emergence and has become
increasingly important over time. Impressive achievements have been obtained in this field …

Detection of amyloid-β fibrils using track-etched nanopores: Effect of geometry and crowding

N Meyer, N Arroyo, JM Janot, M Lepoitevin… - ACS …, 2021 - ACS Publications
Several neurodegenerative diseases have been linked to proteins or peptides that are
prone to aggregate in different brain regions. Aggregation of amyloid-β (Aβ) peptides is …

Sensing with nanopores and aptamers: a way forward

L Reynaud, A Bouchet-Spinelli, C Raillon, A Buhot - Sensors, 2020 - mdpi.com
In the 90s, the development of a novel single molecule technique based on nanopore
sensing emerged. Preliminary improvements were based on the molecular or biological …

The promise of nanopore technology: Advances in the discrimination of protein sequences and chemical modifications

B Cressiot, L Bacri, J Pelta - Small Methods, 2020 - Wiley Online Library
Only a small percent of human genomic DNA encodes for proteins. Additionally, protein
isoforms variants and chemical modifications are not coded in the genome read by the cell …

Microfluidic and paper-based devices for disease detection and diagnostic research

JM Campbell, JB Balhoff, GM Landwehr… - International journal of …, 2018 - mdpi.com
Recent developments in microfluidic devices, nanoparticle chemistry, fluorescent
microscopy, and biochemical techniques such as genetic identification and antibody capture …

Single-molecule identification of the conformations of human C-reactive protein and its aptamer complex with solid-state nanopores

J Wu, L Liang, M Zhang, R Zhu, Z Wang… - … Applied Materials & …, 2022 - ACS Publications
Human C-reactive protein (CRP) is an established inflammatory biomarker and was proved
to be potentially relevant to disease pathology and cancer progression. A large body of …