[HTML][HTML] Genomic Landscape of Susceptibility to Severe COVID-19 in the Slovenian Population
Determining the genetic contribution of susceptibility to severe SARS-CoV-2 infection
outcomes is important for public health measures and individualized treatment. Through …
outcomes is important for public health measures and individualized treatment. Through …
High production MBL2 polymorphisms protect against COVID-19 complications in critically ill patients: A retrospective cohort study
LV de Andrade, MV de Souza Sá, B Vasconcelos… - Heliyon, 2024 - cell.com
Mannose-binding lectin (MBL) binds to SARS-CoV-2, inhibits infection of susceptible cells,
and activates the complement system via the lectin pathway. In this study, we investigated …
and activates the complement system via the lectin pathway. In this study, we investigated …
The MBL2 genotype relates to COVID-19 severity and may help to select the optimal therapy
F Scialò, G Cernera, S Esposito, B Pinchera… - Clinical Chemistry and …, 2023 - degruyter.com
Abstract Objectives Sars-CoV-2 acute infection is clinically heterogeneous, ranging from
asymptomatic cases to patients with a severe, systemic clinical course. Among the involved …
asymptomatic cases to patients with a severe, systemic clinical course. Among the involved …
Impact of Exon 1 Polymorphism in the MBL2 Gene on MBL Serum Levels and Infection Susceptibility in Acute Lymphoid Leukemia
LC Oliveira, AN Barbosa, LS Mineiro, PHR de Souza… - 2024 - researchsquare.com
Polymorphisms in the MBL2 gene exon 1 can decrease serum levels of mannose-binding
lectin (MBL), increasing the risk of infection in immunocompromised individuals. This study …
lectin (MBL), increasing the risk of infection in immunocompromised individuals. This study …