Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

A plethora of neurological disorders shares a final common deadly pathway known as
excitotoxicity. Among these disorders, ischemic injury is a prominent cause of death and …

Ischemic stroke refers to the disorder of blood supply of local brain tissue caused by various
reasons. It has high morbidity and mortality worldwide. Astrocytes are the most abundant …

Advancements in molecular biology have led to a greater understanding of the individual
proteins responsible for generating cerebral edema. In large part, the study of cerebral …

Astrocytes are key homeostatic regulators in the central nervous system and play important
roles in physiology. After brain damage caused by eg, status epilepticus, traumatic brain …

Brain edema is a potentially fatal pathological state that occurs after brain injuries such as
stroke and head trauma. In the edematous brain, excess accumulation of extracellular fluid …

Astrocytes are the most numerous cell type in the central nervous system. They provide
structural, trophic, and metabolic support to neurons and modulate synaptic activity …

Synaptic inhibition plays a crucial role in regulating neuronal excitability, which is the
foundation of nervous system function. This inhibition is largely mediated by the …

✓ Cerebral edema is caused by a variety of pathological conditions that affect the brain. It is
associated with two separate pathophysiological processes with distinct molecular and …

In the nervous system, the intracellular chloride concentration ([Cl−] i) determines the
strength and polarity of γ-aminobutyric acid (GABA)-mediated neurotransmission.[Cl−] i is …