Recent updates on mechanisms of resistance to 5-fluorouracil and reversal strategies in colon cancer treatment
S Azwar, HF Seow, M Abdullah, M Faisal Jabar… - Biology, 2021 - mdpi.com
Simple Summary Acquired resistance to chemotherapy by cancer cells is the predominant
factor in chemotherapy failure, which ultimately leads to disease progression and death …
factor in chemotherapy failure, which ultimately leads to disease progression and death …
NEAT1 lncRNA and amyotrophic lateral sclerosis
Y Nishimoto, S Nakagawa, H Okano - Neurochemistry international, 2021 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a representative neurological disease that is known to
devastate entire motor neurons within a period of just a few years. Discoveries of the specific …
devastate entire motor neurons within a period of just a few years. Discoveries of the specific …
MAGI2-AS3 and miR-374b-5p as putative regulators of multiple sclerosis via modulating the PTEN/AKT/IRF-3/IFN-β Axis: new clinical insights
Multiple sclerosis (MS) is a chronic disease and one of the leading causes of disability in
young adults. The current study aims to investigate the pathogenesis of MS via studying the …
young adults. The current study aims to investigate the pathogenesis of MS via studying the …
LncRNA LOC105378097 inhibits cardiac mitophagy in natural ageing mice
X Liu, X Bai, H Liu, Y Hong, H Cui… - Clinical and …, 2022 - Wiley Online Library
Background The development of heart ageing is the main cause of chronic disability,
disease and death in the elderly. Ample evidence has established a pivotal role for …
disease and death in the elderly. Ample evidence has established a pivotal role for …
MicroRNA and long noncoding RNA involvement in gout and prospects for treatment
YT Xu, YR Leng, MM Liu, RF Dong, J Bian… - International …, 2020 - Elsevier
MicroRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are both types of noncoding
RNA. They have been demonstrated to be involved in the regulation of various human …
RNA. They have been demonstrated to be involved in the regulation of various human …
What do we know about the role of lncRNAs in multiple sclerosis?
V Nociti, M Santoro - Neural regeneration research, 2021 - journals.lww.com
Multiple sclerosis is a chronic, inflammatory and degenerative disease of the central nervous
system of unknown aetiology although well-defined evidence supports an autoimmune …
system of unknown aetiology although well-defined evidence supports an autoimmune …
Roles of HOTAIR Long Non-coding RNA in Gliomas and Other CNS Disorders
HOX transcript antisense intergenic RNA (HOTAIR) is a long non-coding RNA (lncRNA)
which is increasingly being perceived as a tremendous molecular mediator of brain …
which is increasingly being perceived as a tremendous molecular mediator of brain …
Dysregulation of long noncoding RNA MEG3 and NLRC5 expressions in patients with relapsing-remitting multiple sclerosis: is there any correlation?
S Torkamandi, S Bahrami, T Ghorashi, M Dehani… - Genes & …, 2021 - nature.com
Long noncoding RNA MEG3 and NLRC5 genes are both involved in the immune system
and the regulation of NLRC5 by MEG3 is documented in rheumatoid arthritis. Therefore, we …
and the regulation of NLRC5 by MEG3 is documented in rheumatoid arthritis. Therefore, we …
The multifaceted functions of long non-coding RNA HOTAIR in neuropathologies and its potential as a prognostic marker and therapeutic biotarget
Long non-coding RNAs (lncRNAs) are progressively being perceived as prominent
molecular agents controlling multiple aspects of neuronal (patho) physiology. Amongst …
molecular agents controlling multiple aspects of neuronal (patho) physiology. Amongst …
[Retracted] Regulatory Role of miRNAs and lncRNAs in Gout
J Shu, M Chen, C Ya, R Yang… - … and Mathematical Methods …, 2022 - Wiley Online Library
Objective. To explore the regulatory functions of ceRNA networks in the nosogenesis of gout
and search for potential therapeutic targets. Methods. We searched the GEO database and …
and search for potential therapeutic targets. Methods. We searched the GEO database and …