Neuromechanical principles underlying movement modularity and their implications for rehabilitation

LH Ting, HJ Chiel, RD Trumbower, JL Allen, JL McKay… - Neuron, 2015 - cell.com
Neuromechanical principles define the properties and problems that shape neural solutions
for movement. Although the theoretical and experimental evidence is debated, we present …

Approaches to revealing the neural basis of muscle synergies: a review and a critique

VCK Cheung, K Seki - Journal of neurophysiology, 2021 - journals.physiology.org
The central nervous system (CNS) may produce coordinated motor outputs via the
combination of motor modules representable as muscle synergies. Identification of muscle …

A systematic review on muscle synergies: from building blocks of motor behavior to a neurorehabilitation tool

RE Singh, K Iqbal, G White… - Applied bionics and …, 2018 - Wiley Online Library
The central nervous system (CNS) is believed to utilize specific predefined modules, called
muscle synergies (MS), to accomplish a motor task. Yet questions persist about how the …

Neuromuscular adjustments of gait associated with unstable conditions

G Martino, YP Ivanenko, A d'Avella… - Journal of …, 2015 - journals.physiology.org
A compact description of coordinated muscle activity is provided by the factorization of
electromyographic (EMG) signals. With the use of this approach, it has consistently been …

Physics-based simulations to predict the differential effects of motor control and musculoskeletal deficits on gait dysfunction in cerebral palsy: a retrospective case …

A Falisse, L Pitto, H Kainz, H Hoang… - Frontiers in human …, 2020 - frontiersin.org
Physics-based simulations of walking have the theoretical potential to support clinical
decision-making by predicting the functional outcome of treatments in terms of walking …

Muscle synergy analysis in children with cerebral palsy

L Tang, F Li, S Cao, X Zhang, D Wu… - Journal of neural …, 2015 - iopscience.iop.org
Objective. To explore the mechanism of lower extremity dysfunction of cerebral palsy (CP)
children through muscle synergy analysis. Approach. Twelve CP children were involved in …

[HTML][HTML] Intra-subject consistency during locomotion: Similarity in shared and subject-specific muscle synergies

D Rimini, V Agostini, M Knaflitz - Frontiers in human neuroscience, 2017 - frontiersin.org
Human locomotion is a complex motor task. Previous research hypothesized that muscle
synergies reflect the modular control of muscle groups operated by the Central Nervous …

SimCP: A Simulation Platform to Predict Gait Performance Following Orthopedic Intervention in Children With Cerebral Palsy

L Pitto, H Kainz, A Falisse, M Wesseling… - Frontiers in …, 2019 - frontiersin.org
Gait deficits in cerebral palsy (CP) are often treated with a single-event multi-level surgery
(SEMLS). Selecting the treatment options (combination of bony and soft tissue corrections) …

Muscle synergies in response to biofeedback-driven gait adaptations in children with cerebral palsy

ATC Booth, MM van der Krogt, J Harlaar… - Frontiers in …, 2019 - frontiersin.org
Background Children with cerebral palsy (CP) often show impaired selective motor control
(SMC) that induces limitations in motor function. Children with CP can improve aspects of …

Discovering individual-specific gait signatures from data-driven models of neuromechanical dynamics

TS Winner, MC Rosenberg, K Jain… - PLOS Computational …, 2023 - journals.plos.org
Locomotion results from the interactions of highly nonlinear neural and biomechanical
dynamics. Accordingly, understanding gait dynamics across behavioral conditions and …