[HTML][HTML] Trained immunity in viral infections, Alzheimer's disease and multiple sclerosis: a convergence in type I interferon signalling and IFNβ-1a
Abstract Type I interferon (IFN-I) signalling represents a major target for modulation in a
virus' bid for latency. IFN-I perturbations are also present in such as Alzheimer's disease …
virus' bid for latency. IFN-I perturbations are also present in such as Alzheimer's disease …
Role of ISG15 post-translational modification in immunity against Mycobacterium tuberculosis infection
Z Wang, T Li, Z Gong, J Xie - Cellular Signalling, 2022 - Elsevier
ISG15 encoded by a type I interferon (IFN) inducible gene mediates an important cellular
process called ISGylation. ISGylation emerges as a powerful host tactic against intracellular …
process called ISGylation. ISGylation emerges as a powerful host tactic against intracellular …
The canonical antiviral protein oligoadenylate synthetase 1 elicits antibacterial functions by enhancing IRF1 translation
MK Harioudh, J Perez, L So, M Maheshwari, TS Ebert… - Immunity, 2024 - cell.com
An important property of the host innate immune response during microbial infection is its
ability to control the expression of antimicrobial effector proteins, but how this occurs post …
ability to control the expression of antimicrobial effector proteins, but how this occurs post …
Host transcriptome-guided drug repurposing for COVID-19 treatment: a meta-analysis based approach
T Loganathan, S Ramachandran, P Shankaran… - PeerJ, 2020 - peerj.com
Background Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has been declared a pandemic by the World Health …
syndrome coronavirus 2 (SARS-CoV-2) has been declared a pandemic by the World Health …
[HTML][HTML] MALAT1 is involved in type I IFNs-mediated systemic lupus erythematosus by up-regulating OAS2, OAS3, and OASL
F Gao, Y Tan, H Luo - Brazilian Journal of Medical and Biological …, 2020 - SciELO Brasil
Systemic lupus erythematosus (SLE) is an autoimmune disease associated with an aberrant
activation of immune cells partly due to the dysfunction of cytokines such as type I interferons …
activation of immune cells partly due to the dysfunction of cytokines such as type I interferons …
Contribution of Heptose Metabolites and the cag Pathogenicity Island to the Activation of Monocytes/Macrophages by Helicobacter pylori
L Faass, SC Stein, M Hauke, M Gapp… - Frontiers in …, 2021 - frontiersin.org
The human gastric pathogen Helicobacter pylori activates human epithelial cells by a
particular combination of mechanisms, including NOD1 and ALPK1-TIFA activation. These …
particular combination of mechanisms, including NOD1 and ALPK1-TIFA activation. These …
Arginase 1 expression by macrophages promotes Cryptococcus neoformans proliferation and invasion into brain microvascular endothelial cells
A Hansakon, C Ngamphiw, S Tongsima… - The Journal of …, 2023 - journals.aai.org
Cryptococcal meningoencephalitis caused by Cryptococcus neoformans infection is the
most common cause of death in HIV/AIDS patients. Macrophages are pivotal for the …
most common cause of death in HIV/AIDS patients. Macrophages are pivotal for the …
Spermine enhances the activity of anti-tuberculosis drugs
C Sao Emani, N Reiling - Microbiology Spectrum, 2024 - Am Soc Microbiol
The discovery of molecules that could shorten the treatment period of tuberculosis (TB)
holds the promise of improving the current regimen. Polyamines are organic polycationic …
holds the promise of improving the current regimen. Polyamines are organic polycationic …
Early pregnancy induces expression of STAT1, OAS1 and CXCL10 in ovine spleen
Y Wang, X Han, L Zhang, N Cao, L Cao, L Yang - Animals, 2019 - mdpi.com
Simple Summary Interferon-tau is a maternal recognition factor in ruminants, and spleen
plays an essential role in regulating innate and adaptive immune responses. We found that …
plays an essential role in regulating innate and adaptive immune responses. We found that …
Transcriptional Profiling of Human Peripheral Blood Mononuclear Cells Stimulated by Mycobacterium tuberculosis PPE57 Identifies Characteristic Genes Associated …
F Yi, J Hu, X Zhu, Y Wang, Q Yu, J Deng… - Frontiers in Cellular …, 2021 - frontiersin.org
Proline-glutamic acid (PE)-and proline-proline-glutamic acid (PPE)-containing proteins are
exclusive to Mycobacterium tuberculosis (MTB), the leading cause of tuberculosis (TB). In …
exclusive to Mycobacterium tuberculosis (MTB), the leading cause of tuberculosis (TB). In …