Analysis of single mammalian cells on-chip

CE Sims, NL Allbritton - Lab on a Chip, 2007 - pubs.rsc.org
A goal of modern biology is to understand the molecular mechanisms underlying cellular
function. The ability to manipulate and analyze single cells is crucial for this task. The advent …

Mathematical models of neuronal growth

H Oliveri, A Goriely - Biomechanics and Modeling in Mechanobiology, 2022 - Springer
The establishment of a functioning neuronal network is a crucial step in neural development.
During this process, neurons extend neurites—axons and dendrites—to meet other neurons …

Pollen tube attraction by the synergid cell

T Higashiyama, S Yabe, N Sasaki, Y Nishimura… - Science, 2001 - science.org
In flowering plants, guidance of the pollen tube to the embryo sac (the haploid female
gametophyte) is critical for successful fertilization. The target embryo sac may attract the …

Chemotactic signaling, microglia, and Alzheimer's disease senile plaques: Is there a connection?

M Luca, A Chavez-Ross, L Edelstein-Keshet… - Bulletin of mathematical …, 2003 - Springer
Chemotactic cells known as microglia are involved in the inflammation associated with
pathology in Alzheimer's disease (AD). We investigate conditions that lead to aggregation of …

Cortical axon guidance by the glial wedge during the development of the corpus callosum

T Shu, LJ Richards - Journal of Neuroscience, 2001 - Soc Neuroscience
Growing axons are often guided to their final destination by intermediate targets. In the
developing spinal cord and optic nerve, specialized cells at the embryonic midline act as …

Continuous molecular monitoring of human dermal interstitial fluid with microneedle-enabled electrochemical aptamer sensors

M Friedel, B Werbovetz, A Drexelius, Z Watkins, A Bali… - Lab on a Chip, 2023 - pubs.rsc.org
The ability to continually collect diagnostic information from the body during daily activity has
revolutionized the monitoring of health and disease. Much of this monitoring, however, has …

[图书][B] Computing in nonlinear media and automata collectives

A Adamatzky - 2001 - taylorfrancis.com
Computing in Nonlinear Media and Automata Collectives presents an account of new ways
to design massively parallel computing devices in advanced mathematical models, such as …

Alzheimer's disease: a mathematical model for onset and progression

M Bertsch, B Franchi, N Marcello… - … medicine and biology …, 2017 - academic.oup.com
In this article we propose a mathematical model for the onset and progression of Alzheimer's
disease based on transport and diffusion equations. We regard brain neurons as a …

Defining the concentration gradient of nerve growth factor for guided neurite outgrowth

X Cao, MS Shoichet - Neuroscience, 2001 - Elsevier
The developing axon is believed to navigate towards its target tissue in response to a
concentration gradient of neurotrophic factors, among other diffusible and surface-bound …

Dispersion in porous media in oscillatory flow between flat plates: applications to intrathecal, periarterial and paraarterial solute transport in the central nervous system

M Keith Sharp, RO Carare, BA Martin - Fluids and Barriers of the CNS, 2019 - Springer
Background As an alternative to advection, solute transport by shear-augmented dispersion
within oscillatory cerebrospinal fluid flow was investigated in small channels representing …