Updates on synthesis and biological activities of 1, 3, 4-oxadiazole: A review

Salahuddin, A Mazumder, MS Yar… - Synthetic …, 2017 - Taylor & Francis
The new era of heterocyclic moieties which are developed in the decades plays a very
important role in the treatment of various diseases. Among them are 1, 3, 4-oxadiazoles, a …

[PDF][PDF] Heterocyclic 1, 3, 4-oxadiazole compounds with diverse biological activities: A comprehensive review

S Bala, S Kamboj, A Kumar - J. Pharm. Res, 2010 - researchgate.net
The chemistry of heterocyclic compounds has been an interesting field of study for a long
time. Heterocyclic nucleus 1, 3, 4-oxadiazole constitutes an important class of compounds …

1, 3, 4‐Oxadiazole Derivatives: Synthesis, Characterization, Antimicrobial Potential, and Computational Studies

S Bala, S Kamboj, A Kajal, V Saini… - BioMed research …, 2014 - Wiley Online Library
We report the synthesis and biological assessment of 1, 3, 4‐oxadiazole substituted 24
derivatives as novel, potential antibacterial agents. The structures of the newly synthesized …

Evaluation of 2-indolcarbohydrazones as potent α-glucosidase inhibitors, in silico studies and DFT based stereochemical predictions

M Taha, NH Ismail, K Javaid, S Imran, A Wadood… - Bioorganic …, 2015 - Elsevier
Indolcarbohydrazones 1–28 were synthesized and evaluated for their α-glucosidase
inhibitory potential. A varying degree of inhibitory potential with IC 50 values in the range of …

Synthesis and Evaluation of Novel S-alkyl Phthalimide- and S-benzyl-oxadiazole-quinoline Hybrids as Inhibitors of Monoamine Oxidase and Acetylcholinesterase

BA Khan, SS Hamdani, S Jalil, SA Ejaz, J Iqbal… - Pharmaceuticals, 2022 - mdpi.com
New S-alkyl phthalimide 5a–f and S-benzyl 6a–d analogs of 5-(2-phenylquinolin-4-yl)-1, 3, 4-
oxadiazole-2-thiol (4) were prepared by reacting 4 with N-bromoalkylphthalimide and CF3 …

[PDF][PDF] Various approaches for synthesis of 1, 3, 4-Oxadiazole derivatives and their pharmacological activity

R Singh, A Chouhan - World J Pharm Pharm Sci, 2014 - researchgate.net
Oxadiazole, a five membered heterocyclic has been widely studied by researchers because
of its many important chemical and biological properties. The present study summarizes the …

[HTML][HTML] Synthetic marvels in tuberculosis research: An in-depth review of 1, 3, 4-oxadiazole derivatives as antitubercular agents

I Kapila, A Bharwal, P Sharma, N Choudhary… - European Journal of …, 2024 - Elsevier
Given the growth in drug-resistant and inactive cases of tuberculosis, it is imperative to
develop novel, potent chemicals to treat this deadly illness. Compounds containing …

Synthesis of oxadiazole, imidazole, benzimidazole, cyclohexano analogues of 1, 5-benzodiazepines through phenoxyl/phenylamino linkage

MA Mir - Current Organocatalysis, 2022 - ingentaconnect.com
Aims: The study aims to synthesize oxadiazole, imidazole, benzimidazole, and cyclohexano
analogues of 1, 5-benzodiazepines through phenoxyl/phenylamino linkage. Background: It …

Chemistry of Oxadiazole Analogues: Current Status and Applications

A Jha, A Sen, RR Malla - Russian Journal of Bioorganic Chemistry, 2021 - Springer
Oxadiazoles are heterocyclic compounds in numerous approved, and experimental drugs,
bioactive molecules, liquid crystals, diodes and in solar cell applications. It is one of the …

[PDF][PDF] Review exploring antiinflammatory potential of 1, 3, 4-oxadiazole derivatives as promising lead

S Bala, V Saini, S Kamboj… - Int. J. Pharm. Sci. Rev …, 2012 - researchgate.net
Steroids and non-steroidal antiinflammatory drugs are globally used for reducing
inflammation in the body. 1, 3, 4-Oxadiazoles are five membered heterocyclic compounds …