Introduction Electronic cigarettes'(e-cigarettes) viability as a public health strategy to end
smoking will likely be determined by their ability to mimic the pharmacokinetic profile of a …

Abstract Introduction Both the Tobacco Control Act in the US and Article 9 of the Framework
Convention on Tobacco Control enable governments to directly address the addictiveness …

Monoamine oxidase (MAO) activity is reduced in cigarette smokers and this may promote
the reinforcing actions of nicotine, thereby enhancing the addictive properties of cigarettes …

Reducing the nicotine content in tobacco products is being considered by the FDA as a
policy to reduce the addictiveness of tobacco products. Understanding individual differences …

The WHO Study Group on Tobacco Product Regulation (TobReg) 31is mandated to provide
the WHO Director-General with scientifically sound, evidence-based recommendations for …

Introduction Although nicotine is the primary reinforcing constituent in cigarettes, there is
evidence that other constituents in cigarette smoke may interact with nicotine to reinforce …

Background: Reducing nicotine content in cigarettes and other combustible products to
levels that are not reinforcing or addictive has the potential to substantially reduce tobacco …

Introduction: Although nearly 90% of current smokers initiated tobacco use during
adolescence, little is known about reinforcement by nicotine in adolescents. Researchers …

Background The popularity of electronic cigarettes (ECs) has increased dramatically despite
their unknown health consequences. Because the abuse liability of ECs is one of the …

Background The FDA is considering reducing the nicotine content in tobacco products as a
population-based strategy to reduce tobacco addiction. Research is needed to determine …