Colistin kills bacteria by targeting lipopolysaccharide in the cytoplasmic membrane

A Sabnis, KLH Hagart, A Klöckner, M Becce, LE Evans… - elife, 2021 - elifesciences.org
Colistin is an antibiotic of last resort, but has poor efficacy and resistance is a growing
problem. Whilst it is well established that colistin disrupts the bacterial outer membrane (OM) …

On the interpretation of bioaerosol exposure measurements and impacts on health

H Mbareche, L Morawska… - Journal of the Air & Waste …, 2019 - Taylor & Francis
Bioaerosols are recognized as one of the main transmission routes for infectious diseases
and are responsible for other various types of health effects through inhalation and potential …

Detecting lipopolysaccharide in the cytosol of mammalian cells: Lessons from MD-2/TLR4

JH Barker, JP Weiss - Journal of leukocyte biology, 2019 - academic.oup.com
Proinflammatory immune responses to Gram-negative bacterial lipopolysaccharides (LPS)
are crucial to innate host defenses but can also contribute to pathology. How host cells …

[HTML][HTML] Optimization of bacterial DNA and endotoxin extraction from settled airborne dust

H Amin, IPG Marshall, RJ Bertelsen, IM Wouters… - Science of the Total …, 2023 - Elsevier
Collecting and obtaining sufficient amount of airborne particles for multiple microbial
component assessments can be challenging. A passive dust sampling device, the …

Characterization of inhalable endotoxin, glucan, and dust exposures in Iowa farmers

JF Sauvé, SJ Locke, PR Josse, EM Stapleton… - International journal of …, 2020 - Elsevier
Background The observed deficit of lung cancer in farmers has been partly attributed to
exposure to organic dusts and endotoxins based largely on surrogate metrics. To move …

Imaging-based assessment of lung function in a population cooking indoors with biomass fuel: a pilot study

AS Kizhakke Puliyakote, EM Stapleton… - Journal of Applied …, 2023 - journals.physiology.org
Biomass fuels (wood) are commonly used indoors in underventilated environments for
cooking in the developing world, but the impact on lung physiology is poorly understood …

Plasma claudin-3 is associated with tumor necrosis factor-alpha-induced intestinal endotoxemia in liver disease

ZH Wang, A Wang, Z Gong, I Biviano, H Liu… - Clinics and Research in …, 2019 - Elsevier
Objective To investigate intestinal endotoxemia (IETM), intestinal permeability (IP) and
cytokine activity in patients with liver cirrhosis (LC). Materials and methods Twenty-nine …

Effectiveness of portable HEPA air cleaners on reducing indoor endotoxin, PM10, and coarse particulate matter in an agricultural cohort of children with asthma: A …

AM Riederer, JE Krenz, MI Tchong‐French… - Indoor …, 2021 - Wiley Online Library
We conducted a randomized trial of portable HEPA air cleaners in the homes of children age
6–12 years with asthma in the Yakima Valley, Washington. All families received asthma …

The school inner-city asthma intervention study: design, rationale, methods, and lessons learned

W Phipatanakul, P Koutrakis, BA Coull, CM Kang… - Contemporary clinical …, 2017 - Elsevier
Asthma is the most common chronic disease of childhood in the United States, causes
significant morbidity, particularly in the inner-city, and accounts for billions of dollars in …

[HTML][HTML] Environmental endotoxin exposure and asthma

PS Thorne - The Journal of allergy and clinical immunology, 2021 - ncbi.nlm.nih.gov
Environmental endotoxin is associated with a variety of respiratory diseases that arise in
occupational, agricultural, and domestic settings. Endotoxin refers to lipopolysaccharide …