As a conceptual model of disease mechanisms, a disease map integrates available
knowledge and is applied for data interpretation, predictions and hypothesis generation. It is …

PRL-3 belongs to the PRL phosphatase family. Its physiological role remains unclear, but
many studies have identified that PRL-3 is a marker of cancer progression and shown it to …

Vitamin C (VC), a well-reported antioxidant, is found with beneficial actions of preventing
and treating pneumonia. However, the detailed pharmacological target and mechanism of …

The fruits of Ailanthus altissima Swingle (AS) possess a variety of pharmacological activities.
Its antioxidant activity and the potential mode of action have not yet been investigated. In in …

The lack of integrated resources depicting the complexity of the innate immune response in
cancer represents a bottleneck for high-throughput data interpretation. To address this …

Chronic inflammatory diseases (CIDs), including inflammatory bowel disease (IBD),
rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are thought to emerge …

We present the AsthmaMap, a machine-and human-readable representation of mechanisms
underlying asthma. This is an open project driven by a community of experts in systems …

Technological for the purpose of interlingual communication has gone through tremendous
changes because of mechanical progressions. The significance of two important …

We address the need for modelling and predicting adverse outcomes in immunotoxicology
to improve non-clinical assessments of immunomodulatory therapy safety and efficacy. The …

Detailed maps of the molecular basis of the disease are powerful tools for interpreting data
and building predictive models. Modularity and composability are considered necessary …