Review on natural products databases: where to find data in 2020

M Sorokina, C Steinbeck - Journal of cheminformatics, 2020 - Springer
Natural products (NPs) have been the centre of attention of the scientific community in the
last decencies and the interest around them continues to grow incessantly. As a …

[HTML][HTML] Applications of molecular docking in natural products-based drug discovery

I Asiamah, SA Obiri, W Tamekloe, FA Armah… - Scientific African, 2023 - Elsevier
Natural products have a long history of use in the treatment of various diseases particularly
in developing countries. The use of compounds of natural origin as lead compounds for the …

COCONUT online: collection of open natural products database

M Sorokina, P Merseburger, K Rajan, MA Yirik… - Journal of …, 2021 - Springer
Natural products (NPs) are small molecules produced by living organisms with potential
applications in pharmacology and other industries as many of them are bioactive. This …

The natural products atlas: an open access knowledge base for microbial natural products discovery

JA Van Santen, G Jacob, AL Singh, V Aniebok… - ACS central …, 2019 - ACS Publications
Despite rapid evolution in the area of microbial natural products chemistry, there is currently
no open access database containing all microbially produced natural product structures …

In Silico ADME/Tox Profiling of Natural Products: A Focus on BIOFACQUIM

NA Durán-Iturbide, BI Díaz-Eufracio… - ACS …, 2020 - ACS Publications
Natural products continue to be major sources of bioactive compounds and drug candidates
not only because of their unique chemical structures but also because of their overall …

Health benefits of phytochemicals from Brazilian native foods and plants: Antioxidant, antimicrobial, anti-cancer, and risk factors of metabolic/endocrine disorders …

APA de Carvalho, CA Conte-Junior - Trends in Food Science & Technology, 2021 - Elsevier
Background Brazil has over 40,000 varied plant species rich in phytochemicals, expressing
20% of the world's flora. Due to its immense diversity, Brazil presents a high potential to …

Virtual screening techniques in drug discovery: review and recent applications

SFL da Silva Rocha, CG Olanda… - Current topics in …, 2019 - ingentaconnect.com
The discovery of bioactive molecules is an expensive and time-consuming process and new
strategies are continuously searched for in order to optimize this process. Virtual Screening …

StreptomeDB 3.0: an updated compendium of streptomycetes natural products

AFA Moumbock, M Gao, A Qaseem, J Li… - Nucleic acids …, 2021 - academic.oup.com
Antimicrobial resistance is an emerging global health threat necessitating the rapid
development of novel antimicrobials. Remarkably, the vast majority of currently available …

The potential contribution of the natural products from Brazilian biodiversity to bioeconomy

M Valli, HM Russo, VS Bolzani - Anais da Academia Brasileira de …, 2018 - SciELO Brasil
The development of our society has been based on the use of biodiversity, especially for
medicines and nutrition. Brazil is the nation with the largest biodiversity in the world …

Machine learning approaches for elucidating the biological effects of natural products

R Zhang, X Li, X Zhang, H Qin, W Xiao - Natural Product Reports, 2021 - pubs.rsc.org
Covering: 2000 to 2020 Machine learning (ML) is an efficient tool for the prediction of
bioactivity and the study of structure–activity relationships. Over the past decade, an …