Background: A recent proposal of a randomized trial comparing resection and
radiofrequency ablation (RFA) in a selected subgroup of patients with small resectable …

Colorectal cancer (CRC) is one of the leading causes of cancer-related death. Surgery,
radiotherapy and chemotherapy have been till now the main therapeutic strategies for …

Objective: We studied the influence of complete pathologic response of colorectal cancer
liver metastases to prehepatectomy chemotherapy on long-term survival after hepatectomy …

The risk of cancer recurrence after liver surgery mainly depends on tumor biology, but
preclinical and clinical evidence suggests that the degree of perioperative liver injury plays a …

Disseminated tumor cells (DTCs) spread systemically yet distinct patterns of metastasis
indicate a range of tissue susceptibility to metastatic colonization. Distinctions between …

Liver regeneration after major surgery may activate occult micrometastases and facilitate
tumor growth, leading to liver tumor recurrence. Molecular changes during liver regeneration …

Little is known about which genes mediate metastasis in bladder cancer, which accounts for
much of the mortality of this disease. We used human bladder cancer cell lines to develop …

Background The transdifferentiation of hepatic stellate cells (HSCs) into myofibroblasts is a
major mechanism for stroma development in hepatic metastasis, but their regulatory …

Recent studies have shown that the chemokine stromal cell‐derived factor (SDF)‐1 and its
receptor CXCR4 are involved in the metastatic process of colorectal cancer. The impact of …

Laparoscopic liver resection (LHR) has shown classical advantages of minimally invasive
surgery over open counterpart. In spite of introduction in early 1990's only few centres …