[HTML][HTML] A review of human coronaviruses' receptors: the host-cell targets for the crown bearing viruses
A novel human coronavirus prompted considerable worry at the end of the year 2019. Now,
it represents a significant global health and economic burden. The newly emerged …
it represents a significant global health and economic burden. The newly emerged …
[HTML][HTML] New progresses on cell surface protein HSPA5/BiP/GRP78 in cancers and COVID-19
T Li, J Fu, J Cheng, AA Elfiky, C Wei, J Fu - Frontiers in Immunology, 2023 - frontiersin.org
Heat-shock-protein family A (Hsp70) member 5 (HSPA5), aliases GRP78 or BiP, is a protein
encoded with 654 amino acids by the HSPA5 gene located on human chromosome 9q33. 3 …
encoded with 654 amino acids by the HSPA5 gene located on human chromosome 9q33. 3 …
[HTML][HTML] The chaperone GRP78 is a host auxiliary factor for SARS-CoV-2 and GRP78 depleting antibody blocks viral entry and infection
AJ Carlos, DP Ha, DW Yeh, R Van Krieken… - Journal of Biological …, 2021 - ASBMB
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
the COVID-19 global pandemic, utilizes the host receptor angiotensin-converting enzyme 2 …
the COVID-19 global pandemic, utilizes the host receptor angiotensin-converting enzyme 2 …
[HTML][HTML] The stress-inducible ER chaperone GRP78/BiP is upregulated during SARS-CoV-2 infection and acts as a pro-viral protein
The current Coronavirus global pandemic necessitates the search for novel targets and
therapeutic avenues. Shaban et al. 1 reported the use of an endoplasmic reticulum (ER) …
therapeutic avenues. Shaban et al. 1 reported the use of an endoplasmic reticulum (ER) …
Interference of Chaga mushroom terpenoids with the attachment of SARS-CoV-2; in silico perspective
Finding a potent inhibitor to the pandemic SARS-CoV-2 is indispensable nowadays.
Currently, in-silico methods work as expeditious investigators to screen drugs for possible …
Currently, in-silico methods work as expeditious investigators to screen drugs for possible …
The surge in Covid related mucormycosis
Coronavirus disease 2019 (COVID-19) is a novel systemic disease that affects multiple
organs, with the lungs being most affected. 1-3 Previous studies have demonstrated that …
organs, with the lungs being most affected. 1-3 Previous studies have demonstrated that …
GRP78: A possible relationship of COVID-19 and the mucormycosis; in silico perspective
Mucormycosis is a severe fungal infection reported in many cancer survivors, diabetic and
immune-suppressed patients during organ transplants. A vast spark in the reported COVID …
immune-suppressed patients during organ transplants. A vast spark in the reported COVID …
[HTML][HTML] Serum glucose-regulated protein 78 (GRP78) levels in COVID-19-associated mucormycosis: results of a case–control study
Background In experimental models, the expression of glucose-regulated protein 78
(GRP78) in endothelial cells played a role in the pathogenesis of mucormycosis. However …
(GRP78) in endothelial cells played a role in the pathogenesis of mucormycosis. However …
Targeting SARS‐CoV‐2 with Chaga mushroom: An in silico study toward developing a natural antiviral compound
The novel coronavirus (SARS‐CoV‐2) has caused large‐scale global outbreaks and mainly
mediates host cell entry through the interaction of its spike (S) protein with the human …
mediates host cell entry through the interaction of its spike (S) protein with the human …
[HTML][HTML] SARS-CoV-2 delta variant is recognized through GRP78 host-cell surface receptor, in silico perspective
Different SARS-CoV-2 new variants emerged and spread during the past few months,
sparking infections and death counts. The new variant B. 1.617 (delta variant) sparked in …
sparking infections and death counts. The new variant B. 1.617 (delta variant) sparked in …