No matter what their origin, strain and family, viruses have evolved exquisite strategies to
reach and penetrate specific target cells where they hijack the cellular machinery to express …

Life on earth is dependent on the catalytic activity of a number of different metal ions in their
polypeptide scaffold. Of these metals iron is widely used for catalysis of many reactions by …

Background/Aims: Bone marrow mesenchymal stem cells (MSCs) widely applied for treating
myocardial infarction face survival challenges in the inflammatory and ischemia …

Aims Recent evidence suggests that cardiac progenitor cells (CPCs) may improve cardiac
function after injury. The underlying mechanisms are indirect, but their mediators remain …

In regenerative medicine, clinical imaging is indispensable for characterizing damaged
tissue and for measuring the safety and efficacy of therapy. However, the ability to track the …

Although cellular therapies hold great promise for the treatment of human disease, results
from several initial clinical trials have not shown a level of efficacy required for their use as a …

Despite the decline in US cancer incidence and mortality rates, cancer remains the number
one cause of death for people under the age of 85 and one in four people in the US will die …

Ferritins, highly symmetrical protein nanocages, are reactors for Fe2+ and dioxygen or
hydrogen peroxide that are found in all kingdoms of life and in many different cells of …

Measuring iron content has practical clinical indications in the study of diseases such as
Parkinson's disease, Huntington's disease, ferritinopathies and multiple sclerosis as well as …

Being able to self-renew and differentiate into virtually all cell types, both human embryonic
stem cells (hESCs) and induced pluripotent stem cells (iPSCs) have exciting therapeutic …