An updated review on 1, 2, 3-/1, 2, 4-triazoles: synthesis and diverse range of biological potential
The synthesis of triazoles has attracted a lot of interest in the field of organic chemistry
because of its versatile chemical characteristics and possible biological uses. This review …
because of its versatile chemical characteristics and possible biological uses. This review …
Improvement of the Antioxidant and Antitumor Activities of Benzimidazole-Chitosan Quaternary Ammonium Salt on Drug Delivery Nanogels
B Ma, Q Li, J Zhang, Y Mi, W Tan, Z Guo - Marine Drugs, 2024 - mdpi.com
The present study focused on the design and preparation of acid-responsive benzimidazole-
chitosan quaternary ammonium salt (BIMIXHAC) nanogels for a controlled, slow-release of …
chitosan quaternary ammonium salt (BIMIXHAC) nanogels for a controlled, slow-release of …
[HTML][HTML] Flavonoids and other constituents from Jacaranda mimosifolia: In vitro analysis, molecular docking, and molecular dynamic simulations of antioxidant and anti …
PB Leutcha, H Mamoudou, YON Ditchou… - Biomedicine & …, 2025 - Elsevier
The investigation of the methanol extract of the flowers of Jacaranda mimosifolia led to the
isolation and characterisation of fourteen secondary metabolites (1–14) by the means of …
isolation and characterisation of fourteen secondary metabolites (1–14) by the means of …
Optimizing Linezolid: Transforming It into a Selective MAO-B Inhibitor via a Toxicity-to-Activity Optimization Approach
Linezolid, a widely used oxazolidinone antibiotic, exhibits potent activity against resistant
bacterial infections but is associated with serotonergic toxicity, primarily due to its inhibition …
bacterial infections but is associated with serotonergic toxicity, primarily due to its inhibition …
Synthesis and Antibacterial Activity of Novel Triazolo[4,3-a]pyrazine Derivatives
Z Hu, H Dong, Z Si, Y Zhao, Y Liang - Molecules, 2023 - mdpi.com
Infectious diseases pose a major challenge to human health, and there is an urgent need to
develop new antimicrobial agents with excellent antibacterial activity. A series of novel …
develop new antimicrobial agents with excellent antibacterial activity. A series of novel …
[HTML][HTML] Utilization of environmentally friendly catalyst Fe3O4 from iron rust in the synthesis of spiropiperidine derivative
This study aims to synthesize Fe 3 O 4 nanoparticles using iron rust and evaluate the
catalyst's ability in spiropiperidine synthesis. Fe 3 O 4 was synthesized using the thermal …
catalyst's ability in spiropiperidine synthesis. Fe 3 O 4 was synthesized using the thermal …
Targeting EGFR by Newer 1-(3, 5-Bis ((E)-4-hydroxy-3-methoxystyryl)-1H-pyrazol-1-yl)-2-((substituted phenyl) amino) ethan-1-one Analogues for the Treatment of …
Several curcumin analogues (C01-C03) were prepared in green solvent (water-glycerol; 2: 1
v/v) with boric acid (10% mol solution in glycerol). All the compounds were characterized by …
v/v) with boric acid (10% mol solution in glycerol). All the compounds were characterized by …
Deciphering the cytotoxic and antioxidant potential of 3, 5-disubstituted isoxazole-linked benzimidazolone derivatives
M Adardour, S Drioua, MA Lahcen, I Hdoufane… - Journal of Molecular …, 2025 - Elsevier
A series of new isoxazole derivatives containing a benzimidazolone has been synthesized
by cycloaddition reaction using various nitrile oxides. In all cases, these cycloadditions are …
by cycloaddition reaction using various nitrile oxides. In all cases, these cycloadditions are …
Molecular modelling, cytotoxicity & biological investigation of novel fluorinated diphenylamine chalcone derivatives
A Shah, K Desai, A Bhanusali, N Malek, N Naik… - Journal of Molecular …, 2024 - Elsevier
Abstract A unique series of 1-(3-(3, 4-difluorophenyl) amino) phenyl) ethan-1-one linked
fluorinated diphenylamine chalcones (A1-A7) were synthesized and characterized by NMR …
fluorinated diphenylamine chalcones (A1-A7) were synthesized and characterized by NMR …
[HTML][HTML] Design, Synthesis, enzyme inhibitory activity and molecular docking studies of new 1, 2, 3-triazole linked nucleobases
A Aggarwal, C Vashisth, K Bharti, N Raghav… - Results in Chemistry, 2024 - Elsevier
Abstract Thirteen novel 1, 2, 3-triazole linked nucleobases (5a-m) were designed and
efficiently synthesized as potential human enzyme inhibitors. The target compounds were …
efficiently synthesized as potential human enzyme inhibitors. The target compounds were …