G protein–coupled receptors (GPCRs) constitute the largest family of membrane proteins in
the human genome and are important therapeutic targets. During the last decade, the …

Neutrophils have a critical role in inflammation. Recent studies have identified their
distinctive presence in certain types of atopic dermatitis (AD), yet their exact function remains …

Lung cancer is the leading cause of cancer-related death worldwide. Its high mortality is
partly due to chronic inflammation that accompanies the disease and stimulates cancer …

Parkinson's disease (PD) is a neurodegenerative disorder where misfolded alpha-synuclein-
enriched aggregates called Lewy bodies are central in pathogenesis. No neuroprotective or …

Asthma is a chronic obstructive lung disease characterized by recurrent episodes of
bronchoconstriction and wheezing. Conventional asthma treatment involves the …

Indole is a prestigious heterocyclic skeleton widely found in both naturally-occurring and
biologically active compounds. Pharmaceutical agents containing indole skeleton in their …

Leukotrienes are important pro-inflammatory lipid mediators derived from the arachidonic
acid metabolism. In particular, cysteinyl leukotrienes, namely LTC4, LTD4, and LTE4 are …

Introduction Cough is one of the most common presenting symptoms of COVID‐19, which
can persist for weeks or months. Objective The goal of this study was to evaluate the …

Introduction: Asthma and bronchiectasis appear to be two related diseases and in their
complex inflammatory interaction, the cysteinyl leukotriene/cysteinyl leukotriene receptor 1 …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder, and the etiology is
unknown. Metabolic dysfunction is present in patients with ASD. In the current study …