Sedentary and high‐calorie diets are associated with increased risk of obesity and type 2
diabetes mellitus, while exercise and diet control are also important nondrug treatments for …

We tested the hypothesis that female mice null for uncoupling protein 1 (UCP1) would have
increased susceptibility to Western diet-induced “whitening” of brown adipose tissue (AT) …

Loss of ovarian hormones leads to increased adiposity and insulin resistance (IR),
increasing the risk for cardiovascular and metabolic diseases. The purpose of this study was …

The role of estrogen receptor-α (ERα) signaling in immunometabolic function is established
in females. However, its necessity in males, while appreciated, requires further study …

The relationship between liver interleukin-6 (IL-6) resistance following high-fat diet (HFD)-
induced obesity and glucose intolerance is unclear. The purpose of this study was to assess …

Various endocrine factors contribute to cold‐induced white adipose tissue (WAT) browning,
but glucagon has largely been ignored. The purpose of the current investigation was to …

Beta-3 adrenergic receptor activation via exercise or CL316, 243 (CL) induces white
adipose tissue (WAT) browning, improves glucose tolerance, and reduces visceral adiposity …

Ketogenic diets (KDs) are a popular tool used for weight management. Studies in mice have
demonstrated that KDs reduce food intake, increase energy expenditure and cause weight …

We recently showed that Western diet–induced obesity and insulin resistance promotes
endothelial cortical stiffness in young female mice. Herein, we tested the hypothesis that …

Brown adipose tissue (BAT) is considered protective against obesity and related
cardiometabolic dysfunction. Indeed, activation of BAT improves glucose homeostasis and …