Luciferase-based GloSensor™ cAMP assay: Temperature optimization and application to cell-based kinetic studies

FI Wang, G Ding, GS Ng, SJ Dixon, P Chidiac - Methods, 2022 - Elsevier
G protein-coupled receptors (GPCRs) are an important receptor superfamily and common
therapeutic targets. The second messenger cyclic adenosine monophosphate (cAMP) is a …

Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system

L Rinaldi, R Delle Donne, B Catalanotti… - Nature …, 2019 - nature.com
Activation of G-protein coupled receptors elevates cAMP levels promoting dissociation of
protein kinase A (PKA) holoenzymes and release of catalytic subunits (PKAc). This results in …

Photoreceptor calcium sensor proteins in detergent-resistant membrane rafts are regulated via binding to caveolin-1

VI Vladimirov, EY Zernii, VE Baksheeva, H Wimberg… - Cell Calcium, 2018 - Elsevier
Rod cell membranes contain cholesterol-rich detergent-resistant membrane (DRM) rafts,
which accumulate visual cascade proteins as well as proteins involved in regulation of …

Retracted Article: Differential detection and quantification of cyclic AMP and other adenosine phosphates in live cells

S Das, HS Sarkar, MR Uddin, K Rissanen… - Chemical …, 2017 - pubs.rsc.org
A new naphthol-based rhodamine derivative (NpRD) has been developed for the selective
and differential detection of adenosine 3′, 5′-cyclic monophosphate (cAMP) and …

Synthetic PreImplantation Factor (sPIF) induces posttranslational protein modification and reverses paralysis in EAE mice

S Hayrabedyan, R Shainer, Z Yekhtin, L Weiss… - Scientific reports, 2019 - nature.com
An autoimmune response against myelin protein is considered one of the key pathogenic
processes that initiates multiple sclerosis (MS). The currently available MS disease …

PDE 2015: cAMP signaling, protein kinase A (PKA) and phosphodiesterases (PDEs): how genetics changed the way we look at one of the most studied signaling …

CA Stratakis, F Kelestimur… - Hormone and Metabolic …, 2017 - thieme-connect.com
This special issue of Hormone and Metabolic Research presents the proceedings of the 4th
international workshop (PDE 2015) on cyclic AMP (cAMP)/protein kinase A (PKA) signaling …