Tight junctions (TJ) are intercellular adhesion complexes on epithelial cells and composed
of integral membrane proteins as well as cytosolic adaptor proteins. Tight junction proteins …

Lung ischemia-reperfusion injury (LIRI) and primary graft dysfunction are leading causes of
morbidity and mortality among lung transplant recipients. Although extensive research …

Context Ferulic acid (FA) has antioxidative and anti-inflammatory effects, and is a promising
drug to treat sepsis. Objective To study the therapeutic effect of FA in sepsis-induced acute …

Although mesenchymal stromal (stem) cell (MSC) administration attenuates sepsis-induced
lung injury in pre-clinical models, the mechanism (s) of action and host immune system …

PM2. 5 negatively affects human health, particularly lung injury. However, the role of PM2. 5-
regulated miRNAs in lung injury remains unknown. MiRNA array results showed mmu-miR …

Aims To investigate the role and mechanisms of methyltransferase-like 3 (METTL3) in the
pathogenesis of lipopolysaccharide (LPS)-induced acute lung injury (ALI). Main methods …

Acute respiratory distress syndrome (ARDS) is a severe pulmonary disease, which is one of
the major complications in COVID-19 patients. Dysregulation of the immune system and …

CD95L (also known as FasL or CD178) is a member of the tumor necrosis family (TNF)
superfamily. Although this transmembrane ligand has been mainly considered as a potent …

Abstract Isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate (IDHP) is one of the main
bioactive metabolites of the Chinese medicinal herb Danshen, which can be absorbed into …

Dysfunction of epithelial barrier is crucial for the development of acute lung injury (ALI). This
study was aimed to evaluate the role of glucose transporter 1 (GLUT1) in dysregulation of …