Tetrahydroquinoline is one of the most important simple nitrogen heterocycles, being
widespread in nature and present in a broad variety of pharmacologically active …

Oxidative cyclizations are important transformations that occur widely during natural product
biosynthesis. The transformations from acyclic precursors to cyclized products can afford …

Covering: up to September 2015 Meroterpenoids are hybrid natural products that partially
originate from the terpenoid pathway. The meroterpenoids derived from fungi display quite …

Abstract The 2-His-1-carboxylate facial triad is a widely used scaffold to bind the iron center
in mononuclear nonheme iron enzymes for activating dioxygen in a variety of oxidative …

Enzymatic hydroxylation of activated and nonactivated sp3-carbons attracts keen interest
from the chemistry community as it is one of the most challenging tasks in organic synthesis …

Covering: up to July 2019 Terpene synthases (TSs) are responsible for generating much of
the structural diversity found in the superfamily of terpenoid natural products. These elegant …

Covering: 2009 to 2018. Diterpenoid alkaloids, originating from the amination of natural
tetracyclic diterpenes, are a diverse class of compounds having complex structural features …

Covering: up to 2018 α-Ketoglutarate (αKG, also known as 2-oxoglutarate)-dependent
mononuclear non-haem iron (αKG-NHFe) enzymes catalyze a wide range of biochemical …

Fe (II)/α-ketoglutarate-dependent dioxygenases (α-KGDs) are widespread enzymes in
aerobic biology and serve a remarkable array of biological functions, including roles in …

Isolates of Aspergillus species are able to produce a large number of secondary
metabolites. The profiles of biosynthetic families of secondary metabolites are species …