Helminth allergens, parasite-specific IgE, and its protective role in human immunity

CM Fitzsimmons, FH Falcone, DW Dunne - Frontiers in immunology, 2014 - frontiersin.org
The Th2 immune response, culminating in eosinophilia and IgE production, is not only
characteristic of allergy but also of infection by parasitic worms (helminths). Anti-parasite IgE …

Host‐parasite relationship in cystic echinococcosis: an evolving story

A Siracusano, F Delunardo, A Teggi… - Journal of Immunology …, 2012 - Wiley Online Library
The larval stage of Echinococcus granulosus causes cystic echinococcosis, a neglected
infectious disease that constitutes a major public health problem in developing countries …

Comprehensive analysis of the secreted proteins of the parasite Haemonchus contortus reveals extensive sequence variation and differential immune recognition

AP Yatsuda, J Krijgsveld, AWCA Cornelissen… - Journal of Biological …, 2003 - ASBMB
Haemonchus contortus is a nematode that infects small ruminants. It releases a variety of
molecules, designated excretory/secretory products (ESP), into the host. Although the …

Human cystic echinococcosis: old problems and new perspectives

A Siracusano, A Teggi, E Ortona - … perspectives on infectious …, 2009 - Wiley Online Library
Cystic echinococcosis (CE) is a widespread chronic endemic helminthic disease caused by
infection with metacestodes of the tapeworm Echinococcus granulosus. CE affects humans …

[HTML][HTML] Excretory/secretory products from in vitro-cultured Echinococcus granulosus protoscoleces

VG Virginio, KM Monteiro, F Drumond… - Molecular and …, 2012 - Elsevier
Cystic hydatid disease (CHD) is caused by infection with Echinococcus granulosus
metacestodes and affects humans and livestock. Proteins secreted or excreted by …

Echinococcosis and allergy

DA Vuitton - Clinical reviews in allergy & immunology, 2004 - Springer
The larval stages of Echinococcus granulosus and E. multilocularis are involved in parasitic
diseases in humans: cystic echinococcosis (CE)(“hydatid disease”) and alveolar …

Justified concern or exaggerated fear: the risk of anaphylaxis in percutaneous treatment of cystic echinococcosis—a systematic literature review

A Neumayr, G Troia, C de Bernardis… - PLoS neglected …, 2011 - journals.plos.org
Percutaneous treatment (PT) emerged in the mid-1980s as an alternative to surgery for
selected cases of abdominal cystic echinococcosis (CE). Despite its efficacy and …

Current status and future prospective of vaccine development against Echinococcus granulosus

MM Pourseif, G Moghaddam, N Saeedi, A Barzegari… - Biologicals, 2018 - Elsevier
Cystic echinococcosis (CE) is one of the most important zoonotic parasite diseases in
human, livestock, and wildlife worldwide. Development of effective vaccines against CE …

The evolution of IgE‐mediated type I hypersensitivity and its immunological value

DI Pritchard, FH Falcone, PD Mitchell - Allergy, 2021 - Wiley Online Library
The allergic phenotype manifests itself in a spectrum of troublesome to life‐threatening
diseases, from seasonal hay fever, through the food allergies, atopic eczema, asthma, to …

Immunomodulatory mechanisms during Echinococcus granulosus infection

A Siracusano, R Riganò, E Ortona, E Profumo… - Experimental …, 2008 - Elsevier
The pathologic events that ensue after humans ingest the eggs of Echinococcus granulosus
and continue while cystic echinococcosis develops, provide an excellent example …