Genomic advances have contributed to a proliferation of newborn screening (NBS)
programs. Psychosocial consequences of NBS have been identified as risks to these public …

Abstract β-thalassaemia is one of the most common single-gene inherited conditions in the
world, and thalassaemia carrier screening is the most widely performed genetic screening …

Objective To evaluate the clinical impact of nationwide implementation of genome‐wide non‐
invasive prenatal testing (NIPT) in pregnancies at increased risk for fetal trisomies 21, 18 …

Objective To identify the decision support needs of parents attempting to make an informed
health decision on behalf of a child. Context The first step towards implementing patient …

BACKGROUND. Newborn screening programs now identify children with> 30 biochemical
genetic disorders. False-positive identifications may increase as disorders are added to …

Objective An umbrella review summarising all safety data from systematic reviews of topical
corticosteroids (TCS) in adults and children with atopic eczema. Methods Embase …

Objective. The aims of this systematic review were to integrate the research on posttraumatic
stress (PTS) and posttraumatic stress disorder (PTSD) after termination of pregnancy (TOP) …

Purpose Prenatal screening should enable pregnant women to make informed choices. An
informed decision is defined as being based on sufficient, relevant information and …

This paper explores the ethical implications of introducing non-invasive prenatal diagnostic
tests (NIPD tests) in prenatal screening for foetal abnormalities. NIPD tests are easy and …

Background: The introduction of non-invasive prenatal testing (NIPT) for Down's syndrome
into routine state-funded antenatal care in the UK is approaching. Methods: We conducted …